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Results for "

luteinizing hormone

" in MedChemExpress (MCE) Product Catalog:

49

Inhibitors & Agonists

26

Peptides

3

Recombinant Proteins

2

Isotope-Labeled Compounds

3

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P0243

    Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH

    GnRH Receptor Metabolic Disease
    Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.
    <em>Luteinizing</em> <em>Hormone</em> Releasing <em>Hormone</em> (LH-RH), salmon
  • HY-P1174

    GnRH Receptor Endocrinology
    GnRH Associated Peptide (GAP) (1-13), human is an amino acid peptide fragment derived from GnRH. GAP can increase the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in rat anterior pituitary cells. GAP also inhibit the secretion of prolactin .
    GnRH Associated Peptide (GAP) (1-13), human
  • HY-W041308

    Kathon 930

    GnRH Receptor Endocrinology
    DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR)-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca 2+ signaling cascades .
    DCOIT
  • HY-B1617AS

    Estrogen Receptor/ERR Metabolic Disease Endocrinology
    Zuclomiphene-d4 (citrate) is a deuterium labeled Zuclomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[1][2][3][4].
    Zuclomiphene-d4 citrate
  • HY-E70001

    Others Endocrinology
    Recombinant Human Luteinizing Hormone is a recombinant form of Luteinizing hormone (human) (HY-P2293). Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction .
    Recombinant Human <em>Luteinizing</em> <em>Hormone</em>
  • HY-100812

    GABA Receptor Neurological Disease Endocrinology
    2-Hydroxysaclofen is a potent γ-amino-butyric-acid-B (GABAB) receptor antagonist. 2-Hydroxysaclofen can abolish nicotine-induced hypolocomotor effects and increases the antinociceptive effects. 2-Hydroxysaclofen can stimulate luteinizing hormone (LH) secretion in female rats .
    2-Hydroxysaclofen
  • HY-P3604

    Androgen Receptor Endocrinology
    LH-RH II (chicken) is one of the two forms of luteinizing hormone-releasing hormone (LHRH) the hypothalamus of the domestic hen, which are structural variants of mammalian LHRH. LH-RH II (chicken) enhances gonadotrophin release in the domestic chicken .
    LH-RH II (chicken)
  • HY-B1617A

    Estrogen Receptor/ERR Metabolic Disease Endocrinology
    Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent .
    Zuclomiphene citrate
  • HY-P3606

    GAP (1-24), human

    GnRH Receptor Endocrinology
    GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .
    GnRH Associated Peptide (1-24), human
  • HY-P3605

    GAP (25-53), human

    GnRH Receptor Endocrinology
    GnRH Associated Peptide (GAP) (25-53), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 25-53 fragment (hGAP-25-53), can be used as immunogen to generate antiseras including MC-1, MC-2, and MC-3. GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .
    GnRH Associated Peptide (25-53), human
  • HY-P4568

    GnRH Receptor Endocrinology
    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) .
    (D-Ser4,D-Ser(tBu)6,Azagly10)-LHRH
  • HY-P4577

    GnRH Receptor Endocrinology
    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) .
    (D-Tyr5,D-Ser(tBu)6,Azagly10)-LHRH
  • HY-P4564

    GnRH Receptor Endocrinology
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH is an analogue of luteinizing hormone-releasing hormone (LHRH). LHRH plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) .
    (D-Ser(tBu)6,D-Leu7,Azagly10)-LHRH
  • HY-P4572

    GnRH Receptor Cancer
    (D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist .
    (D-Trp6)-LHRH free acid
  • HY-P4675

    GnRH Receptor Endocrinology
    LHRH (free acid), the luteinizing hormone-releasing hormone, is a neuropeptide hypothalamic. LHRH regulates reproduction. LHRH can be used for the research of cancer .
    LHRH free acid
  • HY-106043

    Wy 40972

    GnRH Receptor Endocrinology
    Lutrelin (Wy 40972) is a luteinizing hormone releasing hormone (LHRH) agonist. Lutrelin inhibits the growth of the endometrial expiant in rats .
    Lutrelin
  • HY-100209

    TAK-013

    GnRH Receptor Endocrinology
    Sufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.1 nM.
    Sufugolix
  • HY-P3666

    GnRH Receptor Endocrinology
    [D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone releasing hormone (LHRH) antagonist .
    [D-Phe2,6, Pro3]-LH-RH
  • HY-107533

    GnRH Receptor Endocrinology
    T-98475 (Compound 26d) is a potent, orally active, non-peptide luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an IC50 of 0.2 nM .
    T-98475
  • HY-100271

    TSH Receptor Endocrinology
    Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC50s of 0.2 and 7.7 μM, respectively.
    Org41841
  • HY-109551

    Others Endocrinology
    Lutropin is a heterodimeric glycoprotein, a hormone produced by gonadotropic cells in the anterior pituitary gland, also known as luteinizing hormone and lutrophin. Lutropin stimulates follicular development, and can be used for researching infertility .
    Lutropin
  • HY-P3668

    GnRH Receptor Endocrinology Cancer
    [D-Lys6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Lys6]-LH-RH acts as a GnRH receptor agonist .
    [D-Lys6]-LH-RH
  • HY-P3672

    GnRH Receptor Endocrinology
    [D-Ala6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Ala6]-LH-RH acts as a GnRH receptor agonist .
    [D-Ala6]-LH-RH
  • HY-P0009

    SB-75

    GnRH Receptor Endocrinology
    Cetrorelix is a potent gonadotrophin-releasing hormone (GnRH) antagonist. Cetrorelix inhibits the endogenous luteinizing hormone surge during ovarian stimulation. Cetrorelix reduces cyclophosphamide induced ovarian follicular destruction in mice .
    Cetrorelix
  • HY-114707

    GnRH Receptor Endocrinology
    Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5 .
    Threonyl-seryl-lysine
  • HY-125611

    GnRH Receptor Endocrinology
    Fluorogestone acetate is a progesterone compound. Fluorogestone acetate inhibits ovulation and synchronizes the estrous cycle in cattle by inhibiting the release of luteinizing hormone (LH) from the pituitary gland .
    Fluorogestone acetate
  • HY-B1617

    Estrogen Receptor/ERR Metabolic Disease
    Zuclomiphene (compound 23) is a potent inhibitor of 17β-Estradiol (HY-B0141) and can inhibit the secretion of luteinizing hormone (LH) .
    Zuclomiphene
  • HY-139303

    Others Endocrinology
    LUF5771 is a potent allosteric recombinant luteinizing hormone (recLH) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy .
    LUF5771
  • HY-130248

    GnRH Receptor Endocrinology
    BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 185 nM and 46nM for hLH (human LH) and rLH (rat LH), respectively. BAY-899 can reduce sex hormone levels .
    BAY-899
  • HY-136942

    GABA Receptor Neurological Disease
    DS1 is a potent GABAA agonist. DS1 increases the activity of serum response element (SRE) and cAMP response element (CRE) promoters. DS1 induces luteinizing hormone beta (LHbeta) and follicle-stimulating hormone beta (FSHbeta) promoter activity .
    DS1
  • HY-P4144

    Phor18-LHRH (338613)

    GnRH Receptor Endocrinology Cancer
    Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is an analogue of luteinizing hormone releasing hormone (LHRH) with antineoplastic activity. Onvitrelin ucalontide is a peptide with sequences of KFAKFAKKFAKFAKKFAKQHWSYGLRPG. Onvitrelin ucalontide effectively inhibits breast cancer, ovarian cancer and prostate cancer xenografts in mouse model .
    Onvitrelin ucalontide
  • HY-120767

    KLH-2109 choline; OBE-2109 choline

    GnRH Receptor Inflammation/Immunology Cancer
    Linzagolix choline (KLH-2109 choline) is a non-peptide gonadotropin-releasing hormone (GnRH) antagonist with oral activity. Linzagolix choline inhibits the release of endogenous gonadotropins such as luteinizing hormone LH and follicle-stimulating hormone FSH by binding to the GnRH receptor within the pituitary gland. This inhibition results in a reduction in the production of sex hormones such as estrogen and progesterone, which in turn affects the course of sex hormone-dependent diseases. Linzagolix choline can be used in the study of sex hormone-dependent diseases such as endometriosis and uterine fibroids .
    Linzagolix choline
  • HY-130249

    GnRH Receptor Endocrinology
    BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 96 nM, 23 nM and 78 nM for hLH (human LH) and rLH (rat LH) and cLH (cynomolgus monkey LH), respectively. BAY-298 can reduce sex hormone levels .
    BAY-298
  • HY-117061

    Prostaglandin Receptor Endocrinology
    Prostaglandin F2α alcohol methyl ether is an alcohol methyl ether G protein-coupled receptor. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord .
    Prostaglandin F2α alcohol methyl ether
  • HY-130660

    Prostamide F2α

    Prostaglandin Receptor Endocrinology
    Prostaglandin F2α ethanolamide (Prostamide F2α) is an ethanolamide-like G protein-coupled receptor. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord .
    Prostaglandin F2α ethanolamide
  • HY-144863

    GnRH Receptor Cancer
    BAY 1214784 is a potent, selective, and orally active antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R). BAY 1214784 is a spiroindoline derivative compound. BAY 1214784 effectively lowers plasma luteinizing hormone levels by up to 49%, at the same time being associated with low pharmacokinetic variability and good tolerability. BAY 1214784 has the potential for the research of uterine fibroids .
    BAY 1214784
  • HY-P3671

    GnRH Receptor Endocrinology
    [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH acts as a GnRH receptor antagonist .
    [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
  • HY-130248B

    GnRH Receptor Others
    (R)-BAY-899 is the R-enantiomer of BAY-899. BAY-899 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 185 nM and 46nM for hLH (human LH) and rLH (rat LH), respectively .
    (R)-BAY-899
  • HY-16168A
    Degarelix
    Maximum Cited Publications
    7 Publications Verification

    GnRH Receptor Apoptosis Endocrinology Cancer
    Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR/LHRHR) antagonist. Degarelix can be used for prostate cancer research .
    Degarelix
  • HY-16168B

    GnRH Receptor Apoptosis Endocrinology Cancer
    Degarelix acetate hydrate is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR/LHRHR) antagonist. Degarelix acetate hydrate can be used for prostate cancer research .
    Degarelix acetate hydrate
  • HY-16168AR

    GnRH Receptor Apoptosis Endocrinology Cancer
    Degarelix (Standard) is the analytical standard of Degarelix. This product is intended for research and analytical applications. Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR/LHRHR) antagonist. Degarelix can be used for prostate cancer research .
    Degarelix (Standard)
  • HY-19464

    Others Endocrinology
    Org 43553 is an orally active and low molecular weight (LMW) luteinizing hormone receptor (LH-R) agonist. Org 43553 shows agonistic activity to human LH and FSH receptors with EC50 values of 3.7 and 110 nM, respectively. Org 43553 can be used for the research of endocrine .
    Org 43553
  • HY-149358

    Neurokinin Receptor Endocrinology
    NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model .
    NK3R-IN-1
  • HY-114810

    Prostaglandin Receptor Endocrinology
    Prostaglandin F2α serinol amide is a serinolamide G protein-coupled receptor that increases calcium levels in human non-small cell lung cancer cells. Prostaglandin F2α is also a luteinizing hormone in sheep and may be a nociceptive mediator in the spinal cord .
    Prostaglandin F2α serinol amide
  • HY-13699

    GnRH Receptor PERK Others
    NBI-42902 is an orally active, potent functional and competitive antagonist of GnRH receptor with an IC50 value of 0.79 nM, a Ki value of 0.56 nM, respectively. NBI-42902 inhibits GnRH-stimulated inositol phosphate (IP) accumulation, Ca 2+ flux, and ERK1/2 activation. NBI-42902 inhibits serum luteinizing hormone (LH) in castrated male macaques. NBI-42902 can be used for research on sex-hormone-related diseases .
    NBI-42902
  • HY-B1617AS1

    Estrogen Receptor/ERR Endocrinology
    Zuclomiphene-d5 (citrate) is the deuterium labeled Zuclomiphene citrate[1]. Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[2][3][4][5].
    Zuclomiphene-d5 citrate
  • HY-P4542

    CRFR Endocrinology
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition .
    (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
  • HY-W679754

    PFTrDA

    Others Infection
    Perfluorotridecanoic acid (PFTrDA) is a perfluoroalkyl substance (PFAS). Embryo larval exposure of PFTrDA induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshβ, in zebrafish when used at concentrations of 0.1 and 0.3 mg/L, respectively. PFTrDA (10 mg/kg) decreases serum testosterone and luteinizing hormone levels, testis palmitic acid, linoleic acid, and oleic acid levels, and the number of Leydig cells in rats in late puberty. Maternal plasma levels of PFTrDA during gestation are positively associated with the development of eczema in female, but not male, infants, and liver levels of PFTrDA are higher in cancerous human livers compared with non-cancerous human livers. It has been found in marine mammals.
    Pentacosafluorotridecanoic Acid
  • HY-P0262A

    Neuropeptide Y Receptor Neurological Disease Metabolic Disease
    Galantide TFA is a reversible and non-specific galanin (GAL) receptor antagonist. Galantide TFA dose-dependently shows antagonism to galanin-induced K + conductance with an IC50 value of 4 nM. Galantide TFA can be used for the research of neurological disease and hormone metabolism research .
    Galantide TFA

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