2. Membrane Transporter/Ion Channel
  3. Calmodulin
  4. W-5 hydrochloride

W-5 hydrochloride is a calmodulin antagonist. W-5 hydrochloride inhibits phosphodiesterase activation with an IC50 value of 240 µM. W-5 hydrochloride can be used as a negative control for W-7 (HY-100912)sup>[2].

For research use only. We do not sell to patients.

W-5 hydrochloride Chemical Structure

W-5 hydrochloride Chemical Structure

CAS No. : 61714-25-8

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W-5 hydrochloride Related Antibodies

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Description

W-5 hydrochloride is a calmodulin antagonist. W-5 hydrochloride inhibits phosphodiesterase activation with an IC50 value of 240 µM. W-5 hydrochloride can be used as a negative control for W-7 (HY-100912)[1]sup>[2].

IC50 & Target

IC50: 240 µM (phosphodiesterase)[1]
In Vitro

W-5 hydrochloride (40 µM; 24 h; incubation with 10 μg/ml of apolipoprotein A-I (apoA-I)) increases the cholesterol and choline-phospholipid efflux[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

W-5 hydrochloride Related Antibodies
Molecular Weight

342.88

Formula

C16H23ClN2O2S
CAS No.
SMILES

O=S(C1=C2C=CC=CC2=CC=C1)(NCCCCCCN)=O.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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W-5 hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

W-561714-25-8W5W 5CalmodulinCaMCalcium-modulated proteinRAW 264 Mouse Macrophage cellsapolipoprotein A-Icholesterolcholine-phospholipidnegative controlInhibitorinhibitorinhibit

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W-5 hydrochloride
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HY-100911
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