2. Oligonucleotides
  3. Antisense Oligonucleotides
  4. Tadnersen sodium

Tadnersen sodium  (Synonyms: BIIB078 sodium; IONIS-C9Rx sodium)

Cat. No.: HY-132581A Purity: 90.06%
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Tadnersen sodium, an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion.

For research use only. We do not sell to patients.

RNA, ([2′-O-(2-methoxyethyl)]G-sp-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C-sp-m5dC-sp-dT-sp-dA-sp-dG-sp-m5dC-sp-dG-sp-m5dC-sp-dG-sp-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]G-[2′-O-(2-methoxyethyl)]A-[2′-O-(2-methoxyethyl)]m5C-sp-[2′-O-(2-methoxyethyl)]m5U-sp-[2′-O-(2-methoxyethyl)]m5C) (ACI), sodium salt

Tadnersen sodium Chemical Structure

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1 mg USD 150 In-stock
5 mg USD 455 In-stock
10 mg USD 735 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Tadnersen sodium:

Tadnersen sodium Related Antibodies

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Description

Tadnersen sodium, an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion[1].

Appearance

Solid

Color

Off-white to light yellow

SMILES

[Tadnersen (sodium)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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Tadnersen sodium Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TadnersenBIIB078IONIS-C9RxBIIB 078BIIB-078OthersAmyotrophicLateralSclerosisALSC9ORF72transcriptsantisenseoligonucleotideInhibitorinhibitorinhibit

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