2. Anti-infection
  3. Parasite
  4. SpdSyn binder-1

SpdSyn binder-1 is a weak binder, which binds in the active site of plasmodium falciparum spermidine synthase. SpdSyn binder-1 can be used for the research of malaria.

For research use only. We do not sell to patients.

SpdSyn binder-1 Chemical Structure

SpdSyn binder-1 Chemical Structure

CAS No. : 251106-30-6

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5 mg USD 80 In-stock
10 mg USD 120 In-stock
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Description

SpdSyn binder-1 is a weak binder, which binds in the active site of plasmodium falciparum spermidine synthase. SpdSyn binder-1 can be used for the research of malaria[1].

IC50 & Target

Plasmodium

 

Molecular Weight

346.43

Formula

C21H22N4O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C2N=CNC2=C1)N3CCN(C/C=C/C4=CC=CC=C4)CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (144.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8866 mL 14.4329 mL 28.8659 mL
5 mM 0.5773 mL 2.8866 mL 5.7732 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8866 mL 14.4329 mL 28.8659 mL 72.1647 mL
5 mM 0.5773 mL 2.8866 mL 5.7732 mL 14.4329 mL
10 mM 0.2887 mL 1.4433 mL 2.8866 mL 7.2165 mL
15 mM 0.1924 mL 0.9622 mL 1.9244 mL 4.8110 mL
20 mM 0.1443 mL 0.7216 mL 1.4433 mL 3.6082 mL
25 mM 0.1155 mL 0.5773 mL 1.1546 mL 2.8866 mL
30 mM 0.0962 mL 0.4811 mL 0.9622 mL 2.4055 mL
40 mM 0.0722 mL 0.3608 mL 0.7216 mL 1.8041 mL
50 mM 0.0577 mL 0.2887 mL 0.5773 mL 1.4433 mL
60 mM 0.0481 mL 0.2405 mL 0.4811 mL 1.2027 mL
80 mM 0.0361 mL 0.1804 mL 0.3608 mL 0.9021 mL
100 mM 0.0289 mL 0.1443 mL 0.2887 mL 0.7216 mL
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SpdSyn binder-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SpdSyn binder-1251106-30-6SpdSyn binder1SpdSyn binder 1Parasitespermidine synthaseweak bindmalariaInhibitorinhibitorinhibit

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