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Tubulin polymerization-IN-64

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-163692
    Tubulin polymerization-IN-64

    		Microtubule/Tubulin Cancer
    Tubulin polymerization-IN-64 (Compound 8a) is an inhibitor for tubulin polymerization by occupying the colchicine binding site of tubulin, with IC50 of 6.9 μM. Tubulin polymerization-IN-64 inhibits proliferations of cancer cells A549, HeLa, HCT116 and HT-29, with IC50s of 2.42, 10.33, 6.28, 5.33 μM, respectively. Tubulin polymerization-IN-64 arrests cell cycle at G2/M phase, induces apoptosis in A549 .
    <em>Tubulin</em> <em>polymerization-IN-64</em>

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