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Pathways Recommended: PROTAC
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PROTAC IRAK4 degrader-10

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-158758
    PROTAC IRAK4 degrader-10

    		PROTACs IRAK Inflammation/Immunology
    PROTAC IRAK4 degrader-10 (compound 10) is an oral active PROTAC based on Cereblon ligand, and induces the degradation of IRAK4 with maximum degradation of 95.94% and the DC50 of 7.68 nM in HEK293 cells (Sturcture Note:(Blue: Cereblon ligand, Black: linker；Pink: IRAK4 ligand) .
    <em>PROTAC</em> <em>IRAK4</em> <em>degrader-10</em>

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