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ECSIT

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

Cat. No. Compare Product Name Species Source
  • HY-P76311
    ECSIT Protein, Human (His)

    Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Protein SITPEC; ECSIT

    		 Human E. coli
    ECSIT protein is an adapter protein in Toll-like receptors, IL-1, and antiviral signaling that crucially activates NF-kappa-B by complexing with TRAF6 and TAK1/MAP3K7, leading to TAK1/MAP3K7 activation and subsequent IKK activation. Ubiquitinated ECSIT interacts with RELA and NFKB1 and translocates to induce NF-kappa-B-dependent gene expression. ECSIT Protein, Human (His) is the recombinant human-derived ECSIT protein, expressed by E. coli , with N-His labeled tag.

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