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Results for "

Abemaciclib

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16297A
    Abemaciclib
    Maximum Cited Publications
    74 Publications Verification

    LY2835219

    		 CDK Cancer
    Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.
    <em>Abemaciclib</em>
  • HY-126534A
    Abemaciclib metabolite M18 hydrochloride
    1 Publications Verification

    LSN3106729 hydrochloride

    		 Ligands for Target Protein for PROTAC CDK Cancer
    Abemaciclib metabolite M18 (LSN3106729) hydrochloride, the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 hydrochloride and a CRBN ligand have been used to design PROTAC CDK4/6 degrader .
    <em>Abemaciclib</em> metabolite M18 hydrochloride
  • HY-129336
    Abemaciclib metabolite M20
    3 Publications Verification

    LSN3106726

    		 CDK Cancer
    Abemaciclib metabolite M20 (LSN3106726), the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for the treatment of cancer .
    <em>Abemaciclib</em> metabolite M20
  • HY-16297AR
    Abemaciclib (Standard)

    		Cancer
    Abemaciclib (Standard) is the analytical standard of Abemaciclib. This product is intended for research and analytical applications. Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.
    <em>Abemaciclib</em> (Standard)
  • HY-126534
    Abemaciclib metabolite M18

    LSN3106729

    		 Ligands for Target Protein for PROTAC CDK Cancer
    Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader .
    <em>Abemaciclib</em> metabolite M18
  • HY-16297AS
    Abemaciclib-d8

    LY2835219-d8

    		 CDK Cancer
    Abemaciclib-d8 is the deuterium labeled Abemaciclib. Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.
    <em>Abemaciclib</em>-d8
  • HY-128669
    Abemaciclib metabolite M2
    1 Publications Verification

    LSN2839567

    		 CDK Drug Metabolite Cancer
    Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s of 1.2 and 1.3 nM, respectively. Anti-cancer activity .
    <em>Abemaciclib</em> metabolite M2
  • HY-129336S
    Abemaciclib metabolite M20-d8

    LSN3106726-d8

    		 CDK Cancer
    Abemaciclib metabolite M20-d8 is the deuterium labeled Abemaciclib metabolite M20. Abemaciclib metabolite M20 (LSN3106726), the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor[1].
    <em>Abemaciclib</em> metabolite M20-d8
  • HY-126534S
    Abemaciclib metabolite M18-d8

    LSN3106729-d8

    		 CDK Ligands for Target Protein for PROTAC Cancer
    Abemaciclib metabolite M18-d8 is the deuterium labeled Abemaciclib metabolite M18. Abemaciclib metabolite M18 (LSN3106729), the metabolite of Abemaciclib (HY-16297A), is a CDK inhibitor with antitumor activity. Abemaciclib metabolite M18 and a CRBN ligand have been used to design PROTAC CDK4/6 degrader[1][2].
    <em>Abemaciclib</em> metabolite M18-d8
  • HY-128669S
    Abemaciclib metabolite M2-d6

    LSN2839567-d6

    		 CDK Cancer
    Abemaciclib metabolite M2-d6 is the deuterium labeled Abemaciclib metabolite M2. Abemaciclib metabolite M2 (LSN2839567) is a metabolite of Abemaciclib, acts as a potent CDK4 and CDK6 inhibitor, with IC50s in the range of 1-3 nM. Anti-cancer activity[1][2].
    <em>Abemaciclib</em> metabolite M2-d6
  • HY-16297
    Abemaciclib methanesulfonate
    Maximum Cited Publications
    74 Publications Verification

    LY2835219 methanesulfonate

    		 CDK Cancer
    Abemaciclib methanesulfonate (LY2835219 methanesulfonate) is a selective CDK4/6 inhibitor with IC50s of 2 nM and 10 nM for CDK4 and CDK6, respectively .
    <em>Abemaciclib</em> methanesulfonate

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