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ARM165

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-163677
    ARM165

    		PROTACs PI3K Akt Cancer
    ARM165 is a heterobifunctional molecule. ARM165 degrades the PIK3CG proteins, inhibits PI3Kγ-Akt signaling pathway, and thus exhibits antileukemia efficacy. ARM165 inhibits proliferations of AML cells, with IC50 <1 μM. (Pink: ligand for target protein PI3Kγ inhibitor AZ2 (HY-111570); Black: linker; Blue: ligand for E3 ligase Pomalidomide (HY-10984))
    <em>ARM165</em>
  • HY-163758
    COOH-C3-CONH-C7-COOH

    		PROTAC Linkers Cancer
    COOH-C3-COGN-C7-COOH is a PEG based linker for PROTAC. COOH-C3-COGN-C7-COOH can be used for synthesis of PROTAC Degrader ARM165 (HY-163677) .
    COOH-C3-CONH-C7-COOH
  • HY-163678
    Pomalidomide-CO-C7-NH-CO-C3-COOH

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-CO-C7-NH-CO-C3-COOH is a conjugate of a ligand for E3 ligase and a linker. Pomalidomide-CO-C7-NH-CO-C3-COOH can be used for synthesis of PROTAC degrader ARM165 (HY-163677) .
    Pomalidomide-CO-C7-NH-CO-C3-COOH

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