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AHR antagonist-8

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-163665
    AHR antagonist 8

    		Others Others
    AHR antagonist 8 (compound SG-02) is a regulator of utrophin, a homolog of dystrophin, and an AhR antagonist (Kd: 41.68 nM). Studies have shown that 800 nM of AHR antagonist 8 can upregulate utrophin by 2.7 times. AHR antagonist 8 also stimulates increased MyHC expression, suggesting that it has the potential to enhance myogenesis. After ADME evaluation, AHR antagonist 8 also has a certain oral bioavailability .
    <em>AHR</em> <em>antagonist 8</em>

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