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436866-52-3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136679
    TD114-2

    		GSK-3 Neurological Disease Metabolic Disease
    TD114-2 (cmpound 29) is a potent and highly selective inhibitor of glycogen synthase kinase-3β (GSK-3β) (IC50=48 nM). TD114-2 is associated with the hydrogen bond formation of arginine 141 (ARG141) specific to GSK-3β, an amino acid that is often a negatively charged residue in other kinases, which determines the high selectivity of GSK-3β. TD114-2 can be used in the study of diabetes, neurodegenerative diseases and other diseases associated with GSK-3β .
    TD114-2

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