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1-Myristoyl-2-hydroxy-sn-glycero-3-PE

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145547
    1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine

    14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine

    		 Liposome Metabolic Disease
    1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .
    1-<em>Myristoyl</em>-2-<em>hydroxy</em>-sn-<em>glycero</em>-3-phosphoethanolamine
  • HY-W339838
    1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium

    14:0 Lyso PG

    		 Liposome Cancer
    1-Myristoyl-2-hydroxy-sn-glycero-3-PG sodium (14:0 Lyso PG) is a liposome to simulate biological phospholipid membrane. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble payloads can be trapped in the internal aqueous space of liposomes, while lipophilic payloads can partition into and become part of the lipid bilayer. Especially for delivering antisense oligonucleotides, it can overcome problems such as inefficient cellular uptake and rapid loss in the body .
    1-<em>Myristoyl</em>-2-<em>hydroxy</em>-sn-<em>glycero</em>-3-PG sodium

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