G6PD Protein, Human (HEK293, His)

G6PD proteins play a key role in cellular metabolism by catalyzing the rate-limiting step of the oxidative pentose phosphate pathway, which is essential for carbohydrate dissimilation during glycolysis. The primary function of this enzyme is to provide reducing power in the form of NADPH and generate pentose phosphate, supporting essential processes such as fatty acid and nucleic acid synthesis. G6PD Protein, Human (HEK293, His) is the recombinant human-derived G6PD protein, expressed by HEK293 , with C-6*His labeled tag. The total length of G6PD Protein, Human (HEK293, His) is 514 a.a., with molecular weight of 55-62 kDa.

The G6PD (Glucose-6-Phosphate Dehydrogenase) protein is a pivotal enzyme that catalyzes the rate-limiting step in the oxidative pentose-phosphate pathway, offering an alternative route for carbohydrate dissimilation alongside glycolysis. The primary function of G6PD is to provide essential reducing power in the form of NADPH and pentose phosphates, which play critical roles in fatty acid and nucleic acid synthesis. NADPH is crucial for maintaining cellular redox balance and serves as a cofactor for various biosynthetic processes, while pentose phosphates contribute to the synthesis of nucleotides and other cellular components. G6PD's central role in cellular metabolism underscores its significance in supporting anabolic pathways essential for cell growth and proliferation.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-6*His

P11413-1 (A2-L515)

2539  [NCBI]

AEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGLLPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQRLNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEPFGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQANNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGKALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESELDLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPIPYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL

55-62 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.2 μm filtered solution of 20mM Citrate, 15% Trehalose, 150mM NaCl, 0.05% Tween 80, pH5.5.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.