2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Protease Inhibitors
  5. Serpin (Protease Inhibitor)
  6. PAI-1

PAI-1

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Cat. No. Product Name / Synonyms Species Source
  • HY-P71077
    Serpin E1 Protein, Human (HEK293, His)

    Plasminogen Activator Inhibitor 1; PAI; PAI-1; Endothelial Plasminogen Activator Inhibitor; Serpin E1; SERPINE1; PAI1; PLANH1

    		Human HEK293
    Serpin E1 is a serine protease inhibitor that regulates various cellular processes by inhibiting TMPRSS7, tissue-type plasminogen activator (PLAT), and urokinase-type plasminogen activator (PLAU). During fibrinolysis, it downregulates PLAT to control thrombus degradation and acts as a PLAU inhibitor to regulate cell adhesion. Serpin E1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin E1 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P71133
    Serpin E1 Protein, Mouse (HEK293, His)

    Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; Serpin E1; Mr1; Pai1; Planh1;

    		Mouse HEK293
    Serpin E1 protein is a serine protease inhibitor that regulates TMPRSS7 and is a major inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). It can significantly downregulate fibrinolysis and control thrombus degradation. Serpin E1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin E1 protein, expressed by HEK293 , with C-6*His labeled tag.
  • HY-P73655
    Serpin E1 Protein, Rat (HEK293, His)

    Plasminogen activator inhibitor 1; PAI-1; Serpin E1; Serpine1; Planh1

    		Rat HEK293
    Serpin E1 Protein, Rat (HEK293, His) is one important member of the serine proteinase inhibitor E superfamily that plays a crucial role in the fibrinolytic system. The Serpin E1 protein is a single-chain glycoprotein composed of 379 amino acids. The active site of the protein is Arg346-Met347. SERPINE1 encodes plasminogen activator inhibitor type 1 (PAI-1), which serves as the primary inhibitor of urokinase plasminogen activator (uPA) and tissue-type plasminogen activator (tPA). The Serpin E1 protein can quickly inhibit the formation of plasmin. Serpin E1 can be transcribed through several signaling cascades, including pro-fibrogenic and pro-inflammatory pathways. Serpin E1 is a serine proteinase inhibitor, serves as an important regulator of extracellular matrix remodeling. Serpin E1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-His, C-10*His labeled tag. The total length of Serpin E1 Protein, Rat (HEK293, His) is 379 a.a., with molecular weight of 48-60 kDa.
  • HY-P73336
    Serpin E1 Protein, Rat (HEK293, Fc)

    Plasminogen activator inhibitor 1; PAI-1; Serpin E1; Serpine1; Planh1

    		Rat HEK293
    Serpin E1 is a serine protease inhibitor that regulates TMPRSS7 and inhibits tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). It can significantly downregulate fibrinolysis and control thrombus degradation. Serpin E1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Serpin E1 Protein, Rat (HEK293, Fc) is 402 a.a., with molecular weight of ~70 kDa.
Cat. No. Product Name Effect Purity