1. Immunology/Inflammation
  2. Nuclear Factor of activated T Cells (NFAT)
  3. (+)-Syringaresinol

(+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC50 of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia.

For research use only. We do not sell to patients.

(+)-Syringaresinol Chemical Structure

(+)-Syringaresinol Chemical Structure

CAS No. : 21453-69-0

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Based on 1 publication(s) in Google Scholar

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Description

(+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC50 of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia[1][2].

IC50 & Target

IC50: 329.4 μM (NFAT transcription factor)[1]

In Vitro

(+)-Syringaresinol inhibits the growth of P-388 cells, with an ED50 0.41 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

418.44

Formula

C22H26O8

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=C(C=C(C=C1OC)[C@@H]2[C@@]3([C@]([H])(CO2)[C@H](OC3)C4=CC(OC)=C(C(OC)=C4)O)[H])OC

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(+)-Syringaresinol
Cat. No.:
HY-126030
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