2. PI3K/Akt/mTOR
  3. PI3K
  4. PI3K-IN-54

PI3K-IN-54 (compound 10w) 是一种泛 PI3K 抑制剂。PI3K-IN-54 对 p110α、p110β、p110δ 的 IC50 值分别为 0.22 nM、1.4 nM 和 0.38 nM。PI3K-IN-54 可用于癌症研究。

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PI3K-IN-54 Chemical Structure

PI3K-IN-54 Chemical Structure

CAS No. : 1336890-05-1

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PI3K-IN-54 Related Antibodies

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Description

PI3K-IN-54 (compound 10w) 是一种泛 PI3K 抑制剂。PI3K-IN-54 对 p110α、p110β、p110δ 的 IC50 值分别为 0.22 nM、1.4 nM 和 0.38 nM。PI3K-IN-54 可用于癌症研究[1]。

IC50 & Target

p110α

0.22 nM (IC50)

p110β

1.4 nM (IC50)

p110δ

0.38 nM (IC50)

Molecular Weight

462.45

Formula

C20H24F2N8O3
CAS No.
SMILES

FC(C1=NC2=C(N1C3=NC(N4CCOCC4)=NC(N5CCOCC5)=N3)C=C(N)C=C2OC)F
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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PI3K-IN-54 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3K-IN-541336890-05-1PI3KPhosphoinositide 3-kinaseU87MG human glioblastoma tumor xenograft modelU87MG human glioblastoma tumor xenograft model cellNZB5 cellcancer,Inhibitorinhibitorinhibit

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