2. Others Anti-infection
  3. Isotope-Labeled Compounds HSV
  4. Penciclovir-d4

Penciclovir-d4  (Synonyms: BRL 39123-d4; VSA 671-d4)

Cat. No.: HY-17424S Purity: ≥97.0%
COA Handling Instructions

Molarity Calculator

Penciclovir-d4 is the deuterium labeled Penciclovir. Penciclovir is reported to be potent against HSV types 1 and 2 with IC50 of 0.04-1.8 μg/mL and 0.06-4.4 μg/mL, respectively[1][2].

For research use only. We do not sell to patients.

Penciclovir-d<sub>4</sub> Chemical Structure

Penciclovir-d4 Chemical Structure

CAS No. : 1020719-72-5

Size Price Stock Quantity
500 μg USD 150 In-stock

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Based on 1 publication(s) in Google Scholar

Other Forms of Penciclovir-d4:

Penciclovir-d4 Related Antibodies

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Description

Penciclovir-d4 is the deuterium labeled Penciclovir. Penciclovir is reported to be potent against HSV types 1 and 2 with IC50 of 0.04-1.8 μg/mL and 0.06-4.4 μg/mL, respectively[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Penciclovir-d4 Related Antibodies
Molecular Weight

257.28

Formula

C10H11D4N5O3
CAS No.
Unlabeled Cas

39809-25-1
Appearance

Solid

Color

White to light yellow

SMILES

OCC(CO)C([2H])([2H])C([2H])([2H])N1C2=C(C(N=C(N2)N)=O)N=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (97.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 2 mg/mL (7.77 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8868 mL 19.4341 mL 38.8682 mL
5 mM 0.7774 mL 3.8868 mL 7.7736 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

COA (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.8868 mL 19.4341 mL 38.8682 mL 97.1704 mL
5 mM 0.7774 mL 3.8868 mL 7.7736 mL 19.4341 mL
DMSO 10 mM 0.3887 mL 1.9434 mL 3.8868 mL 9.7170 mL
15 mM 0.2591 mL 1.2956 mL 2.5912 mL 6.4780 mL
20 mM 0.1943 mL 0.9717 mL 1.9434 mL 4.8585 mL
25 mM 0.1555 mL 0.7774 mL 1.5547 mL 3.8868 mL
30 mM 0.1296 mL 0.6478 mL 1.2956 mL 3.2390 mL
40 mM 0.0972 mL 0.4859 mL 0.9717 mL 2.4293 mL
50 mM 0.0777 mL 0.3887 mL 0.7774 mL 1.9434 mL
60 mM 0.0648 mL 0.3239 mL 0.6478 mL 1.6195 mL
80 mM 0.0486 mL 0.2429 mL 0.4859 mL 1.2146 mL
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Penciclovir-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Penciclovir-d41020719-72-5BRL 39123-d4VSA 671-d4Isotope-Labeled CompoundsHSVHerpes simplex virusInhibitorinhibitorinhibit

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