1. Anti-infection
  2. Influenza Virus
  3. Oseltamivir acid-d3

Oseltamivir acid-d3  (Synonyms: GS 4071-d3; Ro 64-0802-d3; Oseltamivir carboxylate-d3)

Cat. No.: HY-13318S Purity: ≥98.0%
COA Handling Instructions

Oseltamivir acid-d3 is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

For research use only. We do not sell to patients.

Oseltamivir acid-d<sub>3</sub> Chemical Structure

Oseltamivir acid-d3 Chemical Structure

CAS No. : 1242184-43-5

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1 mg USD 260 In-stock
5 mg USD 910 In-stock
10 mg USD 1450 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Oseltamivir acid-d3 is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

Molecular Weight

287.37

Formula

C14H21D3N2O4

CAS No.
Unlabeled Cas

187227-45-8

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C[C@@H](OC(CC)CC)[C@H](NC(C([2H])([2H])[2H])=O)[C@@H](N)C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

PBS (pH 7.2) : ≥ 10 mg/mL (34.80 mM)

DMSO : ≥ 5 mg/mL (17.40 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4798 mL 17.3992 mL 34.7983 mL
5 mM 0.6960 mL 3.4798 mL 6.9597 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / PBS (pH 7.2) 1 mM 3.4798 mL 17.3992 mL 34.7983 mL 86.9959 mL
5 mM 0.6960 mL 3.4798 mL 6.9597 mL 17.3992 mL
10 mM 0.3480 mL 1.7399 mL 3.4798 mL 8.6996 mL
15 mM 0.2320 mL 1.1599 mL 2.3199 mL 5.7997 mL
PBS (pH 7.2) 20 mM 0.1740 mL 0.8700 mL 1.7399 mL 4.3498 mL
25 mM 0.1392 mL 0.6960 mL 1.3919 mL 3.4798 mL
30 mM 0.1160 mL 0.5800 mL 1.1599 mL 2.8999 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Oseltamivir acid-d3
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