Nudifloramide-d₃

Name: Nudifloramide-d 3
Brand: MedChemExpress
SKU: HY-113432S
Rating: 4.5 (1 reviews)

Cat. No.: HY-113432S Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Nudifloramide-d₃ (2PY-d3) is the deuterium labeled Nudifloramide. Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro[1].

For research use only. We do not sell to patients.

Nudifloramide-d<sub>3</sub> Chemical Structure

Nudifloramide-d₃ Chemical Structure

CAS No. : 1207384-48-2

Size	Price	Stock	Quantity
1 mg	USD 350	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 950	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Nudifloramide-d₃:

Nudifloramide In-stock
Nudifloramide-d₆ Get quote

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

155.17

Formula

C₇H₅D₃N₂O₂

CAS No.

1207384-48-2

Unlabeled Cas

701-44-0

Appearance

Solid

Color

White to off-white

SMILES

C(N)(=O)C1=CN(C([2H])([2H])[2H])C(=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

H2O : 33.33 mg/mL (214.80 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.4445 mL	32.2227 mL	64.4454 mL
5 mM	1.2889 mL	6.4445 mL	12.8891 mL
10 mM	0.6445 mL	3.2223 mL	6.4445 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (248 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Rutkowski B, et al. N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? Kidney Int Suppl. 2003 May;(84):S19-21. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H2O	1 mM	6.4445 mL	32.2227 mL	64.4454 mL	161.1136 mL
	5 mM	1.2889 mL	6.4445 mL	12.8891 mL	32.2227 mL
	10 mM	0.6445 mL	3.2223 mL	6.4445 mL	16.1114 mL
	15 mM	0.4296 mL	2.1482 mL	4.2964 mL	10.7409 mL
	20 mM	0.3222 mL	1.6111 mL	3.2223 mL	8.0557 mL
	25 mM	0.2578 mL	1.2889 mL	2.5778 mL	6.4445 mL
	30 mM	0.2148 mL	1.0741 mL	2.1482 mL	5.3705 mL
	40 mM	0.1611 mL	0.8056 mL	1.6111 mL	4.0278 mL
	50 mM	0.1289 mL	0.6445 mL	1.2889 mL	3.2223 mL
	60 mM	0.1074 mL	0.5370 mL	1.0741 mL	2.6852 mL
	80 mM	0.0806 mL	0.4028 mL	0.8056 mL	2.0139 mL
	100 mM	0.0644 mL	0.3222 mL	0.6445 mL	1.6111 mL