2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Normetanephrine-d3 hydrochloride

Normetanephrine-d3 hydrochloride  (Synonyms: (±)-Normetanephrine-d3 (hydrochloride); DL-Normetanephrine-d3 (hydrochloride); (Rac)-Normetanephrine-d3 (hydrochloride))

Cat. No.: HY-W008794S Purity: 99.62%
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Normetanephrine-d3 (hydrochloride) is the deuterium labeled Normetanephrine hydrochloride. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE)[1].

For research use only. We do not sell to patients.

Normetanephrine-d<sub>3</sub> hydrochloride Chemical Structure

Normetanephrine-d3 hydrochloride Chemical Structure

CAS No. : 1085333-97-6

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1 mg USD 350 In-stock
5 mg USD 950 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Normetanephrine-d3 hydrochloride:

Normetanephrine-d3 hydrochloride Related Antibodies

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Description

Normetanephrine-d3 (hydrochloride) is the deuterium labeled Normetanephrine hydrochloride. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Normetanephrine-d3 hydrochloride Related Antibodies
Molecular Weight

222.68

Formula

C9H11D3ClNO3
CAS No.
Unlabeled Cas

1011-74-1
Appearance

Solid

Color

White to off-white

SMILES

NC([2H])([2H])C(C1=CC(OC)=C(C=C1)O)([2H])O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (449.07 mM; Need ultrasonic)

DMSO : 20.83 mg/mL (93.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4907 mL 22.4537 mL 44.9075 mL
5 mM 0.8981 mL 4.4907 mL 8.9815 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.4907 mL 22.4537 mL 44.9075 mL 112.2687 mL
5 mM 0.8981 mL 4.4907 mL 8.9815 mL 22.4537 mL
10 mM 0.4491 mL 2.2454 mL 4.4907 mL 11.2269 mL
15 mM 0.2994 mL 1.4969 mL 2.9938 mL 7.4846 mL
20 mM 0.2245 mL 1.1227 mL 2.2454 mL 5.6134 mL
25 mM 0.1796 mL 0.8981 mL 1.7963 mL 4.4907 mL
30 mM 0.1497 mL 0.7485 mL 1.4969 mL 3.7423 mL
40 mM 0.1123 mL 0.5613 mL 1.1227 mL 2.8067 mL
50 mM 0.0898 mL 0.4491 mL 0.8981 mL 2.2454 mL
60 mM 0.0748 mL 0.3742 mL 0.7485 mL 1.8711 mL
80 mM 0.0561 mL 0.2807 mL 0.5613 mL 1.4034 mL
H2O 100 mM 0.0449 mL 0.2245 mL 0.4491 mL 1.1227 mL
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Normetanephrine-d3 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Normetanephrine-d31085333-97-6(±)-Normetanephrine-d3DL-Normetanephrine-d3(Rac)-Normetanephrine-d3Endogenous MetaboliteInhibitorinhibitorinhibit

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