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  4. Monodes(N-carboxymethyl)valine Daclatasvir TFA

Monodes(N-carboxymethyl)valine Daclatasvir TFA  (Synonyms: Daclatasvir Impurity A TFA)

Cat. No.: HY-133246A Purity: 99.89%
COA Handling Instructions

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Monodes(N-carboxymethyl)valine Daclatasvir TFA (Daclatasvir Impurity A TFA) is the TFA salt form of Monodes(N-carboxymethyl)valine Daclatasvir (HY-133246). Monodes(N-carboxymethyl)valine Daclatasvir TFA is the main degradation product of Daclatasvir (HY-10466). Daclatasvir is a potent HCV NS5A protein inhibitor.

For research use only. We do not sell to patients.

Monodes(N-carboxymethyl)valine Daclatasvir TFA Chemical Structure

Monodes(N-carboxymethyl)valine Daclatasvir TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 182 In-stock
5 mg USD 400 In-stock
10 mg   Get quote  
50 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Monodes(N-carboxymethyl)valine Daclatasvir TFA:

Monodes(N-carboxymethyl)valine Daclatasvir TFA Related Antibodies

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Description

Monodes(N-carboxymethyl)valine Daclatasvir TFA (Daclatasvir Impurity A TFA) is the TFA salt form of Monodes(N-carboxymethyl)valine Daclatasvir (HY-133246). Monodes(N-carboxymethyl)valine Daclatasvir TFA is the main degradation product of Daclatasvir (HY-10466). Daclatasvir is a potent HCV NS5A protein inhibitor[1].

Molecular Weight

695.73

Formula

C35H40F3N7O5
Appearance

Solid

Color

White to off-white

SMILES

COC(N[C@@H](C(C)C)C(N(CCC1)[C@@H]1C2=NC(C3=CC=C(C4=CC=C(C5=CNC([C@H]6NCCC6)=N5)C=C4)C=C3)=CN2)=O)=O.OC(C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (143.73 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4373 mL 7.1867 mL 14.3734 mL
5 mM 0.2875 mL 1.4373 mL 2.8747 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4373 mL 7.1867 mL 14.3734 mL 35.9335 mL
5 mM 0.2875 mL 1.4373 mL 2.8747 mL 7.1867 mL
10 mM 0.1437 mL 0.7187 mL 1.4373 mL 3.5933 mL
15 mM 0.0958 mL 0.4791 mL 0.9582 mL 2.3956 mL
20 mM 0.0719 mL 0.3593 mL 0.7187 mL 1.7967 mL
25 mM 0.0575 mL 0.2875 mL 0.5749 mL 1.4373 mL
30 mM 0.0479 mL 0.2396 mL 0.4791 mL 1.1978 mL
40 mM 0.0359 mL 0.1797 mL 0.3593 mL 0.8983 mL
50 mM 0.0287 mL 0.1437 mL 0.2875 mL 0.7187 mL
60 mM 0.0240 mL 0.1198 mL 0.2396 mL 0.5989 mL
80 mM 0.0180 mL 0.0898 mL 0.1797 mL 0.4492 mL
100 mM 0.0144 mL 0.0719 mL 0.1437 mL 0.3593 mL
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Monodes(N-carboxymethyl)valine Daclatasvir TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monodes(N-carboxymethyl)valine DaclatasvirDaclatasvir Impurity AHCVHepatitis C virusdegradationmetaboliteInhibitorinhibitorinhibit

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