Methimazole-d₃

Cat. No.: HY-B0208S Purity: 99.00%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Methimazole-d₃ is a deuterium labeled Methimazole. Methimazole is an antithyroid agent used for the treatment of the hyperthyroidism in humans and animals[1].

For research use only. We do not sell to patients.

Methimazole-d<sub>3</sub> Chemical Structure

Methimazole-d₃ Chemical Structure

CAS No. : 1160932-07-9

Size	Price	Stock	Quantity
1 mg	USD 680	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Methimazole-d₃:

Methimazole In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Methimazole-d₃ is a deuterium labeled Methimazole. Methimazole is an antithyroid agent used for the treatment of the hyperthyroidism in humans and animals[1].

Molecular Weight

117.19

Formula

C₄H₃D₃N₂S

CAS No.

1160932-07-9

Unlabeled Cas

60-56-0

Appearance

Solid

Color

White to off-white

SMILES

S=C1NC=CN1C([2H])([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (853.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (426.66 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.5332 mL	42.6658 mL	85.3315 mL
5 mM	1.7066 mL	8.5332 mL	17.0663 mL
10 mM	0.8533 mL	4.2666 mL	8.5332 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.00%

Select Batch:

Data Sheet (275 KB) SDS (251 KB)

COA (255 KB) HNMR (220 KB) RP-HPLC (283 KB) LCMS (100 KB)

Handling Instructions (2659 KB)

References

[1]. Tatara MR, et al. Effects of long-term oral administration of methimazole on femur and tibia properties in male Wistar rats. Biomed Pharmacother. 2017 Oct;94:124-128. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H2O / DMSO	1 mM	8.5332 mL	42.6658 mL	85.3315 mL	213.3288 mL
	5 mM	1.7066 mL	8.5332 mL	17.0663 mL	42.6658 mL
	10 mM	0.8533 mL	4.2666 mL	8.5332 mL	21.3329 mL
	15 mM	0.5689 mL	2.8444 mL	5.6888 mL	14.2219 mL
	20 mM	0.4267 mL	2.1333 mL	4.2666 mL	10.6664 mL
	25 mM	0.3413 mL	1.7066 mL	3.4133 mL	8.5332 mL
	30 mM	0.2844 mL	1.4222 mL	2.8444 mL	7.1110 mL
	40 mM	0.2133 mL	1.0666 mL	2.1333 mL	5.3332 mL
	50 mM	0.1707 mL	0.8533 mL	1.7066 mL	4.2666 mL
	60 mM	0.1422 mL	0.7111 mL	1.4222 mL	3.5555 mL
	80 mM	0.1067 mL	0.5333 mL	1.0666 mL	2.6666 mL
	100 mM	0.0853 mL	0.4267 mL	0.8533 mL	2.1333 mL