2. Membrane Transporter/Ion Channel
  3. Chloride Channel
  4. Lubiprostone (hemiketal)

Lubiprostone (hemiketal)  (Synonyms: RU-0211 (hemiketal); SPI-0211 (hemiketal))

Cat. No.: HY-B0680
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Lubiprostone (hemiketal) (RU-0211 (hemiketal)) is a selective chloride channel 2 (CLCN2) activator. Lubiprostone (hemiketal) is used to treat chronic idiopathic constipation and opioid-induced constipation by activating CLCN2 channels to increase chloride ion secretion in the intestine, thereby increasing intestinal fluid secretion and enhancing intestinal peristalsis. Lubiprostone (hemiketal) can be used in the study of chronic constipation and cancer.

For research use only. We do not sell to patients.

Lubiprostone (hemiketal) Chemical Structure

Lubiprostone (hemiketal) Chemical Structure

CAS No. : 333963-40-9

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5 mg USD 60 Get quote 2 - 3 weeks 2 - 3 weeks 1 - 2 weeks
10 mg USD 90 Get quote 2 - 3 weeks 2 - 3 weeks 1 - 2 weeks
25 mg USD 180 Get quote 2 - 3 weeks 2 - 3 weeks 1 - 2 weeks
50 mg USD 290 Get quote 2 - 3 weeks 2 - 3 weeks 1 - 2 weeks
100 mg USD 450 Get quote 2 - 3 weeks 2 - 3 weeks 1 - 2 weeks
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Lubiprostone (hemiketal) Related Antibodies

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Description

Lubiprostone (hemiketal) (RU-0211 (hemiketal)) is a selective chloride channel 2 (CLCN2) activator. Lubiprostone (hemiketal) is used to treat chronic idiopathic constipation and opioid-induced constipation by activating CLCN2 channels to increase chloride ion secretion in the intestine, thereby increasing intestinal fluid secretion and enhancing intestinal peristalsis. Lubiprostone (hemiketal) can be used in the study of chronic constipation and cancer[1].

Molecular Weight

390.46

Formula

C20H32F2O5
CAS No.
SMILES

CCCCC(F)([C@@]1(O[C@@]2([H])[C@]([C@H](C(C2)=O)CCCCCCC(O)=O)([H])CC1)O)F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Lubiprostone (hemiketal) Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lubiprostone (hemiketal)333963-40-9RU-0211 (hemiketal) SPI-0211 (hemiketal)Chloride ChannelCl− ChannelsExcitatory regulationconstipationactivatorESCCIFNCLCN2Inhibitorinhibitorinhibit

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