2. Others Metabolic Enzyme/Protease
  3. Fluorescent Dye Carbonic Anhydrase
  4. GZ22-4

GZ22-4 is a near-infrared (NIR) fluorescent probe. GZ22-4 shows high affinity for carbonic anhydrase IX (CAIX), with a Kd of 0.2 nM. GZ22-4 can be used for the research of visualize CAIX-positive tumors.

For research use only. We do not sell to patients.

GZ22-4 Chemical Structure

GZ22-4 Chemical Structure

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GZ22-4 Related Antibodies

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Description

GZ22-4 is a near-infrared (NIR) fluorescent probe. GZ22-4 shows high affinity for carbonic anhydrase IX (CAIX), with a Kd of 0.2 nM. GZ22-4 can be used for the research of visualize CAIX-positive tumors[1].

IC50 & Target

CA Ⅸ

0.2 nM (Kd)

CA I

 

CA Ⅱ

200 nM (Kd)

CA XII

80 nM (Kd)

Molecular Weight

1860.21

Formula

C88H126F3N6NaO24S4
SMILES

O=S(CCCC[N+]1=C(/C=C/C(CCC/2)=C(OC3=CC=C(CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCS(C4=C(NC5CCCCCCC5)C(F)=C(S(N)(=O)=O)C(F)=C4F)(=O)=O)=O)=O)C=C3)C2=C\C=C6C(C)(C)C(C=CC=C7)=C7N\6CCCCS([O-])(=O)=O)C(C)(C)C8=C1C=CC=C8)(O[Na])=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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GZ22-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GZ22-4Fluorescent DyeCarbonic AnhydraseCarbonate dehydrataseNIRcarbonic anhydrase IXCAIXtumorInhibitorinhibitorinhibit

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