Glutathione arsenoxide TFA (Synonyms: GSAO TFA)

Cat. No.: HY-130588A: FAQs
Data Sheet Handling Instructions

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Glutathione arsenoxide (GSAO) TFA is a potential anticancer agent and a tumour metabolism inhibitor. Glutathione arsenoxide TFA targets Mitochondrial endomycin nucleotide transferase (ANT). Glutathione arsenoxide TFA causes cell proliferation arrest and cell death. Glutathione arsenoxide TFA can be used to identify cell-surface proteins, such as Protein disulphide isomerase.

For research use only. We do not sell to patients.

Glutathione arsenoxide TFA Chemical Structure

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Other Forms of Glutathione arsenoxide TFA:

Glutathione arsenoxide Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

662.42

Formula

C₂₀H₂₆AsF₃N₄O₁₁S

SMILES

O=C(O)CNC([C@H](CSCC(NC1=CC=C([As](O)O)C=C1)=O)NC(CC[C@@H](C(O)=O)N)=O)=O.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

DMSO : 31.25 mg/mL (47.18 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5096 mL	7.5481 mL	15.0962 mL
5 mM	0.3019 mL	1.5096 mL	3.0192 mL
10 mM	0.1510 mL	0.7548 mL	1.5096 mL

View the Complete Stock Solution Preparation Table

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Park D, et al. The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase. Cancer Cell Int. 2012 Mar 26;12(1):11. [Content Brief]

[2]. Habeck M. Australian scientists design novel antiangiogenic weapon[J]. The Lancet Oncology, 2000, 1(4): 199.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5096 mL	7.5481 mL	15.0962 mL	37.7404 mL
	5 mM	0.3019 mL	1.5096 mL	3.0192 mL	7.5481 mL
	10 mM	0.1510 mL	0.7548 mL	1.5096 mL	3.7740 mL
	15 mM	0.1006 mL	0.5032 mL	1.0064 mL	2.5160 mL
	20 mM	0.0755 mL	0.3774 mL	0.7548 mL	1.8870 mL
	25 mM	0.0604 mL	0.3019 mL	0.6038 mL	1.5096 mL
	30 mM	0.0503 mL	0.2516 mL	0.5032 mL	1.2580 mL
	40 mM	0.0377 mL	0.1887 mL	0.3774 mL	0.9435 mL

Glutathione arsenoxide TFA Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glutathione arsenoxideGSAOMitochondrial MetabolismMitochondrial endomycin nucleotide transferaseANTproliferation arrestProtein disulphide isomeraseInhibitorinhibitorinhibit

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