TAGLN2 - transgelin 2 Gene

Homo sapiens

Also known as HA1756

Gene ID: 8407 | Gene type: protein coding

About TAGLN2

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,918,111-159,925,507 (from NCBI)

This gene has 5 transcripts (splice variants), 150 orthologues and 5 paralogues. Ubiquitous expression in lung (RPKM 268.8), stomach (RPKM 231.0) and 25 other tissues.

Summary

The protein encoded by this gene is similar to the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The specific function of this protein has not yet been determined, although it is thought to be a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]

TAGLN2 Products(3)

mRNA	Protein	Name
NM_001277223.2	NP_001264152.1	transgelin-2 isoform b
NM_001277224.2	NP_001264153.1	transgelin-2 isoform a
NM_003564.3	NP_003555.1	transgelin-2 isoform b

TAGLN2 Protein Structure

Calponin

0
100
199 a.a.

Protein Preferred Names

Protein Names

transgelin-2

SM22-alpha homolog

Related Diseases

Diseases

Alias

Barrett'S Adenocarcinoma

Barrett Adenocarcinoma

Adenocarcinoma Arising In Barrett'S Mucosa

Maxillary Sinus Cancer

Malignant Neoplasm Of Antrum	Malignant Tumor Of The Maxillary Sinus
Maxillary Sinus Carcinoma	Cancer Of Maxillary Sinus
Maxillary Sinus Neoplasms

Maxillary Sinus Squamous Cell Carcinoma

Epidermoid Carcinoma Of The Maxillofacial Sinus

Esophagus Adenocarcinoma

Esophageal Adenocarcinoma	Oesophageal Adenocarcinoma
Adenocarcinoma Of Esophagus	Adenocarcinoma Of The Esophagus

Neural Tube Defects

Spina Bifida	Neural Tube Defect
NTD	Neural Tube Defects, Susceptibility To
Spinal Dysraphism	Spina Bifida, Susceptibility To
Rachischisis	Cleft Spine
Open Spine	Hydrocele Spinalis
Neural Tube Defect Nos	Sb - [Spina Bifida]
Spinal Hernia Nos	Spinal Fissure Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14187	TAGLN2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TAGLN2	VGNC	VGNC:65944
Canis familiaris	TAGLN2	VGNC	VGNC:47094
Mus musculus	TAGLN2	MGD	MGI:1312985
Bos taurus	TAGLN2	VGNC	VGNC:35586
Rattus norvegicus	TAGLN2	RGD	RGD:1310840
Others	TAGLN2	NCBI

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