Pi4kb - phosphatidylinositol 4-kinase beta Gene

Rattus norvegicus

Also known as Pik4cb

Gene ID: 81747 | Gene type: protein coding

About Pi4kb

Primary_assembly 2: 182,540,567-182,588,488 forward strand.mRatBN7.2:CM026975.1

This gene has 6 transcripts (splice variants), 213 orthologues, 9 paralogues and is associated with 8 phenotypes. Biased expression in Adrenal (RPKM 175.8), Kidney (RPKM 157.8) and 9 other tissues.

Summary

Enables 1-phosphatidylinositol 4-kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and phosphatidylinositol-mediated signaling. Located in cytosol and plasma membrane. Orthologous to human PI4KB (phosphatidylinositol 4-kinase beta). [provided by Alliance of Genome Resources, Apr 2022]

Pi4kb Products(1)

mRNA	Protein	Name
NM_031083.2	NP_112345.1	phosphatidylinositol 4-kinase beta

Pi4kb Protein Structure

PI4KB_NTD

PI4Kc_III_beta

0
200
400
600
800
862 a.a.

Protein Preferred Names

Protein Names

phosphatidylinositol 4-kinase beta

PI4K-beta	PI4Kbeta
catalytic phosphatidylinositol 4-kinase beta	phosphatidylinositol 4-kinase, catalytic, beta polypeptide
ptdIns 4-kinase beta

Related Agents

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108313	T-00127_HEV1	Inhibitor	99.97%	Unkown
HY-22055B	AN-12-H5 intermediate-1		99.34%	Unkown
HY-100603	GSK-F1	Inhibitor	95.00%	Unkown
HY-120900	AN-12-H5	Inhibitor	98.03%	Unkown
HY-W047496	AN-12-H5 intermediate-2		≥97.0%	Unkown
HY-RS10469	PI4KB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS10470	Pi4kb Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS10471	Pi4kb Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W451820	AN-12-H5 intermediate-3		95.82%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pi4kb	NCBI	NCBI:5298

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