2. Gene
  3. TMC7 - transmembrane channel like 7 Gene

TMC7 - transmembrane channel like 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 79905 | Gene type: protein coding

About TMC7

Cytogenetic location: 16p12.3 Genomic coordinates (GRCh38): 16:18,983,934-19,063,942 (from NCBI)

This gene has 5 transcripts (splice variants), 192 orthologues and 7 paralogues. Broad expression in testis (RPKM 4.7), brain (RPKM 4.0) and 15 other tissues.

Summary

Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in ion transmembrane transport. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMC7 Products(6)

mRNA Protein Name
NM_001160364.2 NP_001153836.1 transmembrane channel-like protein 7 isoform b
NM_001300732.2 NP_001287661.1 transmembrane channel-like protein 7 isoform c
NM_001324263.1 NP_001311192.1 transmembrane channel-like protein 7 isoform d
NM_001324265.1 NP_001311194.1 transmembrane channel-like protein 7 isoform e
NM_001324268.1 NP_001311197.1 transmembrane channel-like protein 7 isoform d
NM_024847.4 NP_079123.3 transmembrane channel-like protein 7 isoform a

TMC7 Protein Structure

TMC

TMC: TMC domain (486 - 597)

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  • 600
  • 723 a.a.
Protein Preferred Names Protein Names

transmembrane channel-like protein 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14627 TMC7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus TMC7 MGD MGI:2443317
Macaca mulatta TMC7 VGNC VGNC:79367
Felis catus TMC7 VGNC VGNC:66237
Bos taurus TMC7 VGNC VGNC:35923
Canis familiaris TMC7 VGNC VGNC:47426
Rattus norvegicus TMC7 RGD RGD:1564267