TMEM91 - transmembrane protein 91 Gene

Homo sapiens

Also known as DSPC3; IFITMD6

Gene ID: 641649 | Gene type: protein coding

About TMEM91

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:41,363,947-41,384,083 (from NCBI)

This gene has 14 transcripts (splice variants), 149 orthologues and 3 paralogues. Broad expression in bone marrow (RPKM 6.3), testis (RPKM 5.0) and 25 other tissues.

Summary

Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle and membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM91 Products(8)

mRNA	Protein	Name
NM_001042595.3	NP_001036060.1	transmembrane protein 91 isoform b
NM_001098821.2	NP_001092291.1	transmembrane protein 91 isoform a
NM_001098822.2	NP_001092292.1	transmembrane protein 91 isoform c
NM_001098823.2	NP_001092293.1	transmembrane protein 91 isoform d
NM_001098824.2	NP_001092294.1	transmembrane protein 91 isoform e
NM_001098825.2	NP_001092295.1	transmembrane protein 91 isoform c
NM_001369862.1	NP_001356791.1	transmembrane protein 91 isoform b
NM_001369864.1	NP_001356793.1	transmembrane protein 91 isoform c

TMEM91 Protein Structure

CD225

0
100
172 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 91

dispanin subfamily C member 3

Related Diseases

Diseases

Alias

Osteogenesis Imperfecta, Type V

Osteogenesis Imperfecta Type 5	OI5
Osteogenesis Imperfecta Type V	Oi Type 5
Oi Type V	Oi, Type V
Oi With Calcification In Interosseous Membranes	Type V Oi
Osteogenesis Imperfecta 5	Oi-V

Lung Mucoepidermoid Carcinoma

Mucoepidermoid Carcinoma Of Lung

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14747	TMEM91 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TMEM91	RGD	RGD:2323264
Felis catus	TMEM91	VGNC	VGNC:66371
Bos taurus	TMEM91	VGNC	VGNC:36126
Mus musculus	TMEM91	MGD	MGI:2443589

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