SYNJ2BP - synaptojanin 2 binding protein Gene

Homo sapiens

Also known as ARIP2; OMP25

Gene ID: 55333 | Gene type: protein coding

About SYNJ2BP

Cytogenetic location: 14q24.2 Genomic coordinates (GRCh38): 14:70,366,499-70,417,090 (from NCBI)

This gene has 2 transcripts (splice variants), 194 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 23.3), duodenum (RPKM 20.4) and 24 other tissues.

Summary

Predicted to enable type II activin receptor binding activity. Involved in several processes, including negative regulation of endothelial cell migration; negative regulation of sprouting angiogenesis; and regulation of signal transduction. Located in mitochondrion. Is integral component of mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]

SYNJ2BP Products(1)

mRNA	Protein	Name
NM_018373.3	NP_060843.2	synaptojanin-2-binding protein

SYNJ2BP Protein Structure

PDZ

0
100
145 a.a.

Protein Preferred Names

Protein Names

synaptojanin-2-binding protein

activin receptor interacting protein 5

Related Diseases

Diseases

Alias

Brucellosis

Mediterranean Fever	Malta Fever
Undulant Fever	Gibraltar Fever
Bang'S Disease	Maltese Fever
Cyprus Fever	Rock Fever
Brucellosis Infection	Brucella Infection

Colorectal Cancer, Hereditary Nonpolyposis, Type 7

HNPCC7	Hereditary Nonpolyposis Colorectal Cancer Type 7
Hereditary Non-Polyposis Colorectal Cancer 7	Cancer, Colorectal, Nonpolyposis, Hereditary, Type 7

Intellectual Developmental Disorder With Short Stature And Behavioral Abnormalities

IDDSSBA

Trench Fever

His-Werner Disease	Quintan Fever
Shin Bone Fever	Wolhynian Fever
Tibialgic Fever	Bartonellosis Due To Bartonella Quintana Infection
Febris Quintata	Five Day Fever
Fever Due To Rickettsia Quintana	Febris Quintana
Fever Due To Bartonella Quintana	Fever Due To Rochalimaea Quintana
Meuse Fever

Bacillary Angiomatosis

Angiomatosis, Bacillary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14095	SYNJ2BP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SYNJ2BP	RGD	RGD:69400
Mus musculus	SYNJ2BP	MGD	MGI:1344347

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