2. Gene
  3. THAP4 - THAP domain containing 4 Gene

THAP4 - THAP domain containing 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PP238; CGI-36; Nb(III)

Gene ID: 51078 | Gene type: protein coding

About THAP4

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:241,584,405-241,637,576 (from NCBI)

This gene has 5 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in testis (RPKM 14.3), heart (RPKM 13.9) and 25 other tissues.

Summary

Enables several functions, including heme binding activity; identical protein binding activity; and peroxynitrite isomerase activity. Involved in nitrate metabolic process and tyrosine metabolic process. [provided by Alliance of Genome Resources, Apr 2022]

THAP4 Products(2)

mRNA Protein Name
NM_001164356.2 NP_001157828.1 peroxynitrite isomerase THAP4 isoform 2
NM_015963.6 NP_057047.4 peroxynitrite isomerase THAP4 isoform 1

THAP4 Protein Structure

THAP

THAP: THAP domain (4 - 90)

DUF1794

DUF1794: Domain of unknown function (DUF1794) (421 - 575)

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  • 577 a.a.
Protein Preferred Names Protein Names

peroxynitrite isomerase THAP4

THAP domain-containing protein 4

Related Diseases

Diseases Alias
Venous Hemangioma
Chromosome 2q37 Deletion Syndrome

Albright Hereditary Osteodystrophy-Like Syndrome

2q37 Microdeletion Syndrome

Brachydactyly-Intellectual Disability Syndrome

Deletion 2q37

2q37 Deletion Syndrome

Brachydactyly-Mental Retardation Syndrome

Bdmr

Albright Hereditary Osteodystrophy Type 3

Del(2)(Q37)

Monosomy 2q37qter

Albright'S Hereditary Osteodystrophy-Like Syndrome

Monosomy 2q37

Chromosome Deletion Syndrome 2q37
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14475 THAP4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta THAP4 VGNC VGNC:99410
Mus musculus THAP4 MGD MGI:1914276
Felis catus THAP4 VGNC VGNC:80379
Rattus norvegicus THAP4 RGD RGD:1359473
Canis familiaris THAP4 VGNC VGNC:59098
Bos taurus THAP4 VGNC VGNC:55691