2. Gene
  3. ARL5A - ADP ribosylation factor like GTPase 5A Gene

ARL5A - ADP ribosylation factor like GTPase 5A Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ARL5; ARFLP5

Gene ID: 26225 | Gene type: protein coding

About ARL5A

Cytogenetic location: 2q23.3 Genomic coordinates (GRCh38): 2:151,798,797-151,828,421 (from NCBI)

This gene has 7 transcripts (splice variants), 212 orthologues and 30 paralogues. Ubiquitous expression in thyroid (RPKM 27.2), heart (RPKM 19.5) and 25 other tissues.

Summary

The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. With its distinctive nuclear/nucleolar localization and interaction with HP1alpha, the protein is developmentally regulated and may play a role(s) in nuclear dynamics and/or signaling cascades during embryonic development. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

ARL5A Products(3)

mRNA Protein Name
NM_001037174.2 NP_001032251.1 ADP-ribosylation factor-like protein 5A isoform 2
NM_012097.4 NP_036229.1 ADP-ribosylation factor-like protein 5A isoform 1
NM_177985.3 NP_817114.2 ADP-ribosylation factor-like protein 5A isoform 2

ARL5A Protein Structure

Arf

Arf: ADP-ribosylation factor family (12 - 174)

  • 0
  • 100
  • 179 a.a.
Protein Preferred Names Protein Names

ADP-ribosylation factor-like protein 5A

ADP-ribosylation factor-like 5

Related Diseases

Diseases Alias
Mucinous Stomach Adenocarcinoma

Mucinous Adenocarcinoma Of The Stomach

Mucinous Gastric Adenocarcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00991 ARL5A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ARL5A VGNC VGNC:80139
Macaca mulatta ARL5A VGNC VGNC:70017
Canis familiaris ARL5A VGNC VGNC:38115
Bos taurus ARL5A VGNC VGNC:26147
Mus musculus ARL5A MGD MGI:1922673
Rattus norvegicus ARL5A RGD RGD:621327