TENM4 - teneurin transmembrane protein 4 Gene

Homo sapiens

Also known as Doc4; ETM5; ODZ4; TEN4; TNM4; ten-4; Ten-M4

Gene ID: 26011 | Gene type: protein coding

About TENM4

Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:78,652,829-79,441,030 (from NCBI)

This gene has 11 transcripts (splice variants), 204 orthologues, 4 paralogues and is associated with 2 phenotypes. Biased expression in ovary (RPKM 7.7), thyroid (RPKM 3.2) and 8 other tissues.

Summary

The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5. [provided by RefSeq, Oct 2016]

TENM4 Products(1)

mRNA	Protein	Name
NM_001098816.3	NP_001092286.2	teneurin-4

TENM4 Protein Structure

Ten_N

EGF_2

hEGF

RHS_repeat

Tox-GHH

0
500
1000
1500
2000
2500
2769 a.a.

Protein Preferred Names

Protein Names

teneurin-4

downstream of CHOP 4

Related Diseases

Diseases

Alias

Tremor, Hereditary Essential, 5

ETM5	Essential Tremor 5
Essential Tremor, Hereditary, 5	Hereditary Essential Tremor 5
Tremor, Hereditary Essential 5	Tremor, Essential Hereditary, Type 5

Tremor

Medicament-Induced Tremor

Medication-Induced Postural Tremor

Essential Tremor

Benign Essential Tremor	Familial Tremor
Hereditary Essential Tremor	Essential Hereditary Tremor
Shaky Hand Syndrome	Benign Essential Tremor Syndrome
Tremor Hereditary Essential	Essential Tremor, Susceptibility To
Tremor, Hereditary Essential

Cleft Palate, Proliferative Retinopathy, And Developmental Delay

CPPRDD

Tremor, Hereditary Essential, 1

ETM1	Fet1
Essential Tremor 1	Tremor, Familial Essential, 1
Essential Tremor, Hereditary, 1	Hereditary Essential Tremor 1
Tremor Hereditary Essential, 1	Tremor Familial Essential, 1
Tremor, Hereditary Essential 1	Tremor, Essential Hereditary, Type 1

Bardet-Biedl Syndrome 2

BBS2	Bardet-Biedl Syndrome
Bardet-Biedl Syndrome, Type 2	Bbs

Tremor, Hereditary Essential, 4

ETM4	Essential Tremor 4
Essential Tremor, Hereditary, 4	Hereditary Essential Tremor 4
Tremor, Hereditary Essential 4	Tremor, Hereditary Essential, Type 4

Bipolar Disorder

Bipolar Depression	Manic Disorder
Depression, Bipolar	Bipolar Disorder Manic Phase
Depressive-Manic Psych.	Manic Bipolar Affective Disorder
Manic Bipolar I Disorder	Manic Depression
Manic Depressive Disorder	Mixed Bipolar Disorder
Bipolar Affective Disorder	Bipolar Affective Psychosis
Bipolar Spectrum Disorder	Manic Depressive Illness
Depression Bipolar	Bipolar Disorder, Mixed
Major Affective Disorder	Major Affective Disorder 1
Major Affective Disorder 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14365	TENM4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TENM4	VGNC	VGNC:66072
Macaca mulatta	TENM4	VGNC	VGNC:107649
Canis familiaris	TENM4	VGNC	VGNC:54999
Mus musculus	TENM4	MGD	MGI:2447063
Rattus norvegicus	TENM4	RGD	RGD:1304658
Bos taurus	TENM4	VGNC	VGNC:35744

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