TMEM9 - transmembrane protein 9 Gene

Homo sapiens

Also known as DERM4; TMEM9A

Gene ID: 252839 | Gene type: protein coding

About TMEM9

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:201,134,772-201,171,558 (from NCBI)

This gene has 11 transcripts (splice variants), 206 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 25.4), thyroid (RPKM 25.3) and 25 other tissues.

Summary

Involved in intracellular pH reduction; positive regulation of canonical Wnt signaling pathway; and proton-transporting V-type ATPase complex assembly. Located in bounding membrane of organelle; intercellular bridge; and mitotic spindle. [provided by Alliance of Genome Resources, Apr 2022]

TMEM9 Products(9)

mRNA	Protein	Name
NM_001288564.2	NP_001275493.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform a precursor
NM_001288565.2	NP_001275494.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform a precursor
NM_001288566.2	NP_001275495.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform a precursor
NM_001288567.2	NP_001275496.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform a precursor
NM_001288568.2	NP_001275497.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform a precursor
NM_001288569.2	NP_001275498.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform a precursor
NM_001288570.2	NP_001275499.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform b precursor
NM_001288571.2	NP_001275500.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform c precursor
NM_016456.5	NP_057540.1	proton-transporting V-type ATPase complex assembly regulator TMEM9 isoform a precursor

TMEM9 Protein Structure

Tmemb_9

0
100
183 a.a.

Protein Preferred Names

Protein Names

proton-transporting V-type ATPase complex assembly regulator TMEM9

dermal papilla-derived protein 4

Related Diseases

Diseases

Alias

Snail Allergy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14746	TMEM9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TMEM9	RGD	RGD:1307922
Mus musculus	TMEM9	MGD	MGI:1913491
Macaca mulatta	TMEM9	VGNC	VGNC:79162
Bos taurus	TMEM9	VGNC	VGNC:36125
Felis catus	TMEM9	VGNC	VGNC:66370

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