2. Gene
  3. TDRD9 - tudor domain containing 9 Gene

TDRD9 - tudor domain containing 9 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as HLS; SPNE; HIG-1; NET54; SPGF30; C14orf75

Gene ID: 122402 | Gene type: protein coding

About TDRD9

Cytogenetic location: 14q32.33 Genomic coordinates (GRCh38): 14:103,928,456-104,052,667 (from NCBI)

This gene has 7 transcripts (splice variants), 196 orthologues, 18 paralogues and is associated with 2 phenotypes. Biased expression in testis (RPKM 26.4) and thyroid (RPKM 5.7).

Summary

Predicted to enable RNA binding activity. Involved in spermatogenesis. Located in cytoplasm and nucleus. Implicated in spermatogenic failure 30. [provided by Alliance of Genome Resources, Apr 2022]

TDRD9 Products(1)

mRNA Protein Name
NM_153046.3 NP_694591.2 ATP-dependent RNA helicase TDRD9

TDRD9 Protein Structure

DEAD

DEAD: DEAD/DEAH box helicase (138 - 294)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (409 - 500)

HA2

HA2: Helicase associated domain (HA2) (566 - 664)

TUDOR

TUDOR: Tudor domain (904 - 1013)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1382 a.a.
Protein Preferred Names Protein Names

ATP-dependent RNA helicase TDRD9

hypoxia-inducible HIG-1

Related Diseases

Diseases Alias
Spermatogenic Failure 30

SPGF30
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Male Infertility With Azoospermia Or Oligozoospermia Due To Single Gene Mutation
Spermatogenic Failure, Y-Linked, 2

SPGFY2

Spermatogenic Failure, Nonobstructive, Y-Linked

Y-Linked Spermatogenic Failure 2

Azoospermia, Nonobstructive, Y-Linked

Oligozoospermia, Nonobstructive, Y-Linked

Oligospermia, Nonobstructive, Y-Linked

Spermatogenic Arrest, Y-Linked

Nonobstructive Y-Linked Spermatogenic Failure

Spermatogenic Failure Y-Linked 2

Azoospermia Non-Obstructive Y-Linked

Non-Obstructive Azoospermia And Infertility

Oligospermia Non-Obstructive Y-Linked

Oligozoospermia Non-Obstructive Y-Linked

Spermatogenic Arrest Y-Linked

Spermatogenic Failure Nonobstructive Y-Linked
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14339 TDRD9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TDRD9 VGNC VGNC:99264
Felis catus TDRD9 VGNC VGNC:66051
Rattus norvegicus TDRD9 RGD RGD:1306942
Bos taurus TDRD9 VGNC VGNC:35722
Canis familiaris TDRD9 VGNC VGNC:47226
Mus musculus TDRD9 MGD MGI:1921941