2. Gene
  3. Brd9 - bromodomain containing 9 Gene

Brd9 - bromodomain containing 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 105246 | Gene type: protein coding

About Brd9

Chromosome 13: 74,085,930-74,109,014 forward strand.GRCm39:CM001006.3

This gene has 12 transcripts (splice variants), 203 orthologues, 2 paralogues and is associated with 20 phenotypes. Ubiquitous expression in CNS E14 (RPKM 2.2), CNS E18 (RPKM 19.3) and 28 other tissues.

Summary

Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Part of SWI/SNF complex. Is expressed in female reproductive system and urinary system. Orthologous to human BRD9 (bromodomain containing 9). [provided by Alliance of Genome Resources, Apr 2022]

Brd9 Products(4)

mRNA Protein Name
NM_001378948.1 NP_001365877.1 bromodomain-containing protein 9 isoform 4
NM_001308041.2 NP_001294970.1 bromodomain-containing protein 9 isoform 2
NM_001378947.1 NP_001365876.1 bromodomain-containing protein 9 isoform 3
NM_001024508.4 NP_001019679.2 bromodomain-containing protein 9 isoform 1

Brd9 Protein Structure

Bromo_brd7_like

Bromo_brd7_like: cd05513 (139 - 236)

DUF3512

DUF3512: pfam12024 (285 - 464)

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  • 597 a.a.
Protein Preferred Names Protein Names

bromodomain-containing protein 9

Related Agents

Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-114322 VZ185 Inhibitor 98.00% Unkown
HY-153367 FHD-609 Inhibitor 99.15% Unkown
HY-100352 BI-9564 Inhibitor 99.86% Unkown
HY-103632 PROTAC BRD9 Degrader-1 Inhibitor 98.30% Unkown
HY-117690 dBRD9 Degrader 99.89% Unkown
HY-100517 TP-472 Inhibitor 99.52% Unkown
HY-110374 NVS-CECR2-1 Inhibitor 99.40% Unkown
HY-123621 GNE-375 Inhibitor 99.81% Unkown
HY-107477 GSK8573 99.05% Unkown
HY-101121 NI-42 Inhibitor 99.79% Unkown
HY-114205A TP-238 hydrochloride Inhibitor ≥99.0% Unkown
HY-116227 (2S,3R)-LP99 Inhibitor / Unkown
HY-150797 QA-68 Inhibitor / Unkown
HY-149806 Bromodomain IN-2 Inhibitor / Unkown
HY-114205 TP-238 Inhibitor / Unkown
HY-143270 PROTAC BRD9-binding moiety 5 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brd9 NCBI NCBI:65980