2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. Complete Freund's adjuvant (CFA, 1 mg/ml)

Complete Freund's adjuvant (CFA, 1 mg/ml) is an immunoadjuvant emulsified with antigen that can enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA, 1 mg/ml) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA, 1 mg/ml) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA, 1 mg/ml) stimulates a strong and durable immune response and can be used to induce rheumatoid arthritis in rats, and more.

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Complete Freund's adjuvant (CFA, 1 mg/ml) Chemical Structure

Complete Freund's adjuvant (CFA, 1 mg/ml) Chemical Structure

CAS No. : 9007-81-2

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Description

Complete Freund's adjuvant (CFA, 1 mg/ml) is an immunoadjuvant emulsified with antigen that can enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA, 1 mg/ml) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA, 1 mg/ml) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA, 1 mg/ml) stimulates a strong and durable immune response and can be used to induce rheumatoid arthritis in rats, and more[1][2][3].

In Vivo

Complete Freund's adjuvant (1 mg/ml, 0.1 mL; s.c.; once a day for two days) can be used to induce rheumatoid arthritis in Sprague-Dawley rats[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats[3]
Dosage: 1 mg/ml, 0.1 mL
Administration: s.c.; once a day for two days
Result: Increased the index of thymus and spleen.
Decreased the activities of GSH, CAT, SOD and MPO.
Increased the level of IL-1β, IL-6, IL-17, MCP-1, TNF-α, COX-2, 5-LOX, NF-p65, IgG1 and IgG2a.
Reduced level of IL-10.
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Complete Freund's adjuvant (CFA, 1 mg/ml)]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation
References
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Complete Freund's adjuvant (CFA, 1 mg/ml) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Complete Freund's adjuvant (CFA, 1 mg/ml)9007-81-2Toll-like Receptor (TLR)immunityinflammationimmunization-induced animal modelsarthritisCIAEAMexperimental autoimmune myocarditisEATEAUtuberculosis bacillirheumatoid arthritisInhibitorinhibitorinhibit

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