Carnosine conjugated hyalyronate

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Carnosine conjugated hyalyronate is a hyaluronic acid derivative functionalized with the dipeptide carnosine (Carnosine, Car) and has the ability to resist Aβ amyloid aggregation. Carnosine conjugated hyalyronate dissolves amyloid fibrils and reduces Aβ-induced toxicity in vitro. The effectiveness of Carnosine conjugated hyalyronate against amyloid aggregation is directly proportional to the Carnosine loading..

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Carnosine conjugated hyalyronate Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 385	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 770	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1230	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 1950	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Description	Carnosine conjugated hyalyronate is a hyaluronic acid derivative functionalized with the dipeptide carnosine (Carnosine, Car) and has the ability to resist Aβ amyloid aggregation. Carnosine conjugated hyalyronate dissolves amyloid fibrils and reduces Aβ-induced toxicity in vitro. The effectiveness of Carnosine conjugated hyalyronate against amyloid aggregation is directly proportional to the Carnosine loading.^[1].
Molecular Weight	600000(Average)
SMILES	OC[C@H]1O[C@@H](OC)[C@H](NC(C)=O)[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@H]3[C@H](NC(C)=O)[C@@H](O[C@H]4[C@H](O)[C@H](O)[C@H](OC)[C@@H](C(NCCC(N[C@H](C(O[Na])=O)CC5=CNC=N5)=O)=O)O4)[C@H](O)[C@@H](CO)O3)[C@@H](C([O-])=O)O2)[C@@H]1O.[Na+]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Greco V, et al. Hyaluronan-carnosine conjugates inhibit Aβ aggregation and toxicity. Sci Rep. 2020 Sep 29;10(1):15998. [Content Brief]