Autocamtide-3 acetate

Name: Autocamtide-3 acetate
Brand: MedChemExpress
SKU: HY-P3811A
Rating: 4.5 (1 reviews)

Cat. No.: HY-P3811A Purity: 99.62%: FAQs
Data Sheet SDS COA Handling Instructions

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Autocamtide-3 acetate, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca²⁺/calmodulin-dependent kinase II) (CaMK) substrate.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Autocamtide-3 acetate Chemical Structure

Size	Price	Stock	Quantity
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Autocamtide-3 acetate:

Autocamtide-3 Get quote

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Biological Activity
Purity & Documentation
References
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Description

Autocamtide-3 acetate, a 13-amino-acid peptide containing Thr287, is a selective CaMKII (Ca²⁺/calmodulin-dependent kinase II) (CaMK) substrate^[1].

In Vitro

20 μM Autocamtide-3 acetate (H2N-Lys-Lys-Ala-Leu-His-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-COOH), and 5 μL of CaMKII is used in a 50 μL kinase-assay reaction. Autocamtide-3 acetate shows catalytic activity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1508.72 (free acid)

Formula

C₆₇H₁₁₇N₂₁O₂₂.xC₂H₄O₂

Unlabeled Cas

Appearance

Solid

Color

White to off-white

Sequence

Lys-Lys-Ala-Leu-His-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu

Sequence Shortening

KKALHRQETVDAL

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.62%

Select Batch:

Data Sheet (268 KB) SDS (252 KB)

COA (247 KB) RP-HPLC (203 KB) MS (71 KB) Elemental Analysis Report (106 KB)

Handling Instructions (2659 KB)

References

[1]. Mehtap Yilmaz, et al. Phosphorylation at Ser²⁶ in the ATP-binding site of Ca²⁺/calmodulin-dependent kinase II as a mechanism for switching off the kinase activity. Biosci Rep. 2013 Feb 7;33(2):e00024. [Content Brief]