2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. Nuclear Factor of activated T Cells (NFAT) Phosphodiesterase (PDE)
  4. Archangelicin

Archangelicin is an inhibitor for cAMP-phosphodiesterase (cAMP-PDE) with IC50 >400 μM. Archangelicin inhibits nuclear factor of activated T cell (NFAT) with IC50 of 9 μM. Archangelicin exhibits antitumor and anti-inflammatory.

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Archangelicin Chemical Structure

Archangelicin Chemical Structure

CAS No. : 2607-56-9

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Archangelicin Related Antibodies

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Description

Archangelicin is an inhibitor for cAMP-phosphodiesterase (cAMP-PDE) with IC50 >400 μM. Archangelicin inhibits nuclear factor of activated T cell (NFAT) with IC50 of 9 μM. Archangelicin exhibits antitumor and anti-inflammatory[1][2][3].

IC50 & Target

IC50: >400 μM (cAMP-PDE), 9 μM (NFAT)
Molecular Weight

426.46

Formula

C24H26O7
CAS No.
SMILES

C/C=C(C)\C(O[C@H]1[C@@H](C(OC(/C(C)=C\C)=O)(C)C)OC(C=C2)=C1C(O3)=C2C=CC3=O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Archangelicin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Archangelicin2607-56-9Nuclear Factor of activated T Cells (NFAT)Phosphodiesterase (PDE)Angelica atropurpureafuranocoumarinInhibitorinhibitorinhibit

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