X-Neu5Ac sodium (Synonyms: X-NeuNAc)

Cat. No.: HY-32264 Purity: 99.92%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

X-Neu5Ac (sodium) is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a K_m of 0.89 mM for neuraminidase.

For research use only. We do not sell to patients.

X-Neu5Ac sodium Chemical Structure

CAS No. : 160369-85-7

Size	Price	Stock	Quantity
5 mg	USD 46	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 69	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 207	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 310	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 930	In-stock	Estimated Time of Arrival: December 31
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Description

X-Neu5Ac (sodium) is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a K_m of 0.89 mM for neuraminidase.

IC₅₀ & Target

Km: 0.89 mM (neuraminidase)^[1]

In Vitro

X-Neu5Ac (sodium) is a good substrate (K_m=0.89 mM) for neuraminidase and is quite stable under identical conditions in the absence of enzyme^[1]. Staining with X-Neu5Ac and FRV LB is specific for sialidase and useful for quantitative analysis of sialidase activities^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

559.72

Formula

C₁₉H₂₁BrClN₂NaO₉

CAS No.

160369-85-7

Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H](O)[C@@H](O)[C@H]1[C@H](NC(C)=O)[C@@H](O)C[C@](OC2=CNC3=C2C(Cl)=C(Br)C=C3)(C(O[Na])=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 200 mg/mL (357.32 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7866 mL	8.9330 mL	17.8661 mL
5 mM	0.3573 mL	1.7866 mL	3.5732 mL
10 mM	0.1787 mL	0.8933 mL	1.7866 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.92%

Select Batch:

Data Sheet (278 KB) SDS (393 KB)

COA (257 KB) RP-HPLC (207 KB)

Handling Instructions (2659 KB)

References

[1]. Fujii I, et al. X-Neu5Ac: a novel substrate for chromogenic assay of neuraminidase activity in bacterial expression systems. Bioorg Med Chem. 1993 Aug;1(2):147-9. [Content Brief]

[2]. Minami A, et al. Imaging of sialidase activity in rat brain sections by a highly sensitive fluorescent histochemical method. Neuroimage. 2011 Sep 1;58(1):34-40. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.7866 mL	8.9330 mL	17.8661 mL	44.6652 mL
	5 mM	0.3573 mL	1.7866 mL	3.5732 mL	8.9330 mL
	10 mM	0.1787 mL	0.8933 mL	1.7866 mL	4.4665 mL
	15 mM	0.1191 mL	0.5955 mL	1.1911 mL	2.9777 mL
	20 mM	0.0893 mL	0.4467 mL	0.8933 mL	2.2333 mL
	25 mM	0.0715 mL	0.3573 mL	0.7146 mL	1.7866 mL
	30 mM	0.0596 mL	0.2978 mL	0.5955 mL	1.4888 mL
	40 mM	0.0447 mL	0.2233 mL	0.4467 mL	1.1166 mL
	50 mM	0.0357 mL	0.1787 mL	0.3573 mL	0.8933 mL
	60 mM	0.0298 mL	0.1489 mL	0.2978 mL	0.7444 mL
	80 mM	0.0223 mL	0.1117 mL	0.2233 mL	0.5583 mL
	100 mM	0.0179 mL	0.0893 mL	0.1787 mL	0.4467 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

X-Neu5Ac sodium Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

X-Neu5Ac160369-85-7X-NeuNAcOthersInhibitorinhibitorinhibit

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