Terephthalic acid

Name: Terephthalic acid
Brand: MedChemExpress
SKU: HY-W010098
Rating: 4.5 (1 reviews)

Cat. No.: HY-W010098 Pureté: 99.93%: FAQs
Fiche technique SDS COA Instruction de manipulation

Molarity Calculator

Terephthalic acid is one isomer of the three phthalic, a precursor to the polyester PET, used to make clothing and plastic bottles.

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Terephthalic acid Chemical Structure

CAS No. : 100-21-0

Size	Prix	Stock	Quantité

Échantillon gratuit (0.1 - 0.5 mg)		Appliquer maintenant
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	En stock	Estimated Time of Arrival: December 31
Solid
500 mg	USD 50	En stock	Estimated Time of Arrival: December 31
5 g	USD 60	En stock	Estimated Time of Arrival: December 31
10 g		Obtenir un devis
50 g		Obtenir un devis

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Based on 1 publication(s) in Google Scholar

Other Forms of Terephthalic acid:

Terephthalic acid-d₄ In-stock
Terephthalic acid-¹³C₂ In-stock
Terephthalic acid (Standard) Obtenir un devis

Recommandations en vedette

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Activité biologique
Pureté et documentation
Références
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Description

Terephthalic acid is one isomer of the three phthalic, a precursor to the polyester PET, used to make clothing and plastic bottles.

In Vivo

Terephthalic acid can be used in animal modeling to construct mouse tumor models.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

166.13

Formule

C₈H₆O₄

CAS No.

100-21-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)C1=CC=C(C(O)=O)C=C1

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Endogenous metabolite

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvant et solubilité

In Vitro:

DMSO : 20 mg/mL (120.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.0194 mL	30.0969 mL	60.1938 mL
5 mM	1.2039 mL	6.0194 mL	12.0388 mL
10 mM	0.6019 mL	3.0097 mL	6.0194 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2 mg/mL (12.04 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 2 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2 mg/mL (12.04 mM); Clear solution

This protocol yields a clear solution of ≥ 2 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Pureté et documentation

Purity: 99.93%

Select Batch:

Fiche technique (270 KB) SDS (393 KB)

COA (246 KB) RP-HPLC (253 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Heck HD, et al. The induction of bladder stones by terephthalic acid, dimethyl terephthalate, and melamine (2,4,6-triamino-s-triazine) and its relevance to risk assessment. Regul Toxicol Pharmacol. 1985 Sep;5(3):294-313. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.0194 mL	30.0969 mL	60.1938 mL	150.4846 mL
	5 mM	1.2039 mL	6.0194 mL	12.0388 mL	30.0969 mL
	10 mM	0.6019 mL	3.0097 mL	6.0194 mL	15.0485 mL
	15 mM	0.4013 mL	2.0065 mL	4.0129 mL	10.0323 mL
	20 mM	0.3010 mL	1.5048 mL	3.0097 mL	7.5242 mL
	25 mM	0.2408 mL	1.2039 mL	2.4078 mL	6.0194 mL
	30 mM	0.2006 mL	1.0032 mL	2.0065 mL	5.0162 mL
	40 mM	0.1505 mL	0.7524 mL	1.5048 mL	3.7621 mL
	50 mM	0.1204 mL	0.6019 mL	1.2039 mL	3.0097 mL
	60 mM	0.1003 mL	0.5016 mL	1.0032 mL	2.5081 mL
	80 mM	0.0752 mL	0.3762 mL	0.7524 mL	1.8811 mL
	100 mM	0.0602 mL	0.3010 mL	0.6019 mL	1.5048 mL