HAEGT 

HAEGT is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide, and the sequence is His-Ala-Glu-Gly-Thr. HAEGT acts as a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV) 1, in which the N-terminal His-Ala is catalyzed cleavage by DPP-IV. HAEGT can be used in the research of diabetes, obesity^[1].

HAEGT (0-500 μM) is a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV)^[1].
HAEGT can be catalyzed cleavage by DPP-IV with a k_m value of 38 μM, K_cat value of 3.1 S^-1[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

513.50

C₂₀H₃₁N₇O₉

852155-81-8

Solid

White to off-white

His-Ala-Glu-Gly-Thr

HAEGT

O=C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(O)=O)=O)=O)=O)[C@H](CC1=CNC=N1)N

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

• [1]. Lisa M Kopcho, et al. Probing prime substrate binding sites of human dipeptidyl peptidase-IV using competitive substrate approach. Arch Biochem Biophys. 2005 Apr 15;436(2):367-76.  [Content Brief]