1. Membrane Transporter/Ion Channel
  2. CRAC Channel
  3. CRAC intermediate 2

CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis, extracted from patent WO 2013059666A1.

For research use only. We do not sell to patients.

CRAC intermediate 2 Chemical Structure

CRAC intermediate 2 Chemical Structure

CAS No. : 123066-64-8

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10 mM * 1 mL in DMSO
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10 mM * 1 mL in DMSO USD 55 In-stock
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50 mg USD 240 In-stock
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Description

CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis, extracted from patent WO 2013059666A1.

Molecular Weight

295.18

Formula

C11H7F6N3

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

NC1=CC=C(N2N=C(C(F)(F)F)C=C2C(F)(F)F)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 52 mg/mL (176.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3878 mL 16.9388 mL 33.8776 mL
5 mM 0.6776 mL 3.3878 mL 6.7755 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3878 mL 16.9388 mL 33.8776 mL 84.6941 mL
5 mM 0.6776 mL 3.3878 mL 6.7755 mL 16.9388 mL
10 mM 0.3388 mL 1.6939 mL 3.3878 mL 8.4694 mL
15 mM 0.2259 mL 1.1293 mL 2.2585 mL 5.6463 mL
20 mM 0.1694 mL 0.8469 mL 1.6939 mL 4.2347 mL
25 mM 0.1355 mL 0.6776 mL 1.3551 mL 3.3878 mL
30 mM 0.1129 mL 0.5646 mL 1.1293 mL 2.8231 mL
40 mM 0.0847 mL 0.4235 mL 0.8469 mL 2.1174 mL
50 mM 0.0678 mL 0.3388 mL 0.6776 mL 1.6939 mL
60 mM 0.0565 mL 0.2823 mL 0.5646 mL 1.4116 mL
80 mM 0.0423 mL 0.2117 mL 0.4235 mL 1.0587 mL
100 mM 0.0339 mL 0.1694 mL 0.3388 mL 0.8469 mL
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CRAC intermediate 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CRAC intermediate 2
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HY-20588
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