3,3'-Diethyloxacarbocyanine iodide

Name: 3,3'-Diethyloxacarbocyanine iodide
Brand: MedChemExpress
SKU: HY-W040258
Rating: 4.5 (1 reviews)

Cat. No.: HY-W040258 Pureté: 99.79%: FAQs
Fiche technique SDS COA Instruction de manipulation

Molarity Calculator

3,3'-Diethyloxacarbocyanine iodide is a microviscosity probe for micelles and microemulsions.

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3,3'-Diethyloxacarbocyanine iodide Chemical Structure

CAS No. : 905-96-4

Size	Prix	Stock	Quantité
100 mg	USD 50	En stock	Estimated Time of Arrival: December 31
200 mg		Obtenir un devis
500 mg		Obtenir un devis

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Based on 1 publication(s) in Google Scholar

Recommandations en vedette

•Related Small Molecules:

•Related Proteins:

Activité biologique
Pureté et documentation
Références
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Description

3,3'-Diethyloxacarbocyanine iodide is a microviscosity probe for micelles and microemulsions^[1].

Masse moléculaire

460.31

Formule

C₂₁H₂₁IN₂O₂

CAS No.

905-96-4

Appearance

Solid

Color

Purple to purplish red

SMILES

CCN1C2=C(C=CC=C2)O/C1=C/C=C/C(OC3=C4C=CC=C3)=[N+]4CC.[I-]

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvant et solubilité

In Vitro:

DMSO : 20.83 mg/mL (45.25 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1724 mL	10.8622 mL	21.7245 mL
5 mM	0.4345 mL	2.1724 mL	4.3449 mL
10 mM	0.2172 mL	1.0862 mL	2.1724 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Pureté et documentation

Purity: 99.79%

Select Batch:

Fiche technique (274 KB) SDS (251 KB)

COA (252 KB) HNMR (260 KB) LCMS (267 KB)

Instruction de manipulation (2659 KB)

Références

[1]. SaswatiBasu, et al. 3,3′-Diethyloxacarbocyanine iodide: A new microviscosity probe for micelles and microemulsions. Colloids and Surfaces A: Physicochemical and Engineering Aspects.

[2]. E L Sievers, et al. Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate. Blood. 1999 Jun 1;93(11):3678-84. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1724 mL	10.8622 mL	21.7245 mL	54.3112 mL
	5 mM	0.4345 mL	2.1724 mL	4.3449 mL	10.8622 mL
	10 mM	0.2172 mL	1.0862 mL	2.1724 mL	5.4311 mL
	15 mM	0.1448 mL	0.7241 mL	1.4483 mL	3.6207 mL
	20 mM	0.1086 mL	0.5431 mL	1.0862 mL	2.7156 mL
	25 mM	0.0869 mL	0.4345 mL	0.8690 mL	2.1724 mL
	30 mM	0.0724 mL	0.3621 mL	0.7241 mL	1.8104 mL
	40 mM	0.0543 mL	0.2716 mL	0.5431 mL	1.3578 mL