2. Natural Products
  3. Endogenous metabolite Ketones, Aldehydes, Acids
  4. 11S(12R)-EET

11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters.

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11S(12R)-EET Chemical Structure

11S(12R)-EET Chemical Structure

CAS No. : 123931-40-8

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Other Forms of 11S(12R)-EET:

11S(12R)-EET Related Antibodies

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Description

11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters[1].

Molecular Weight

320.47

Formula

C20H32O3
CAS No.
SMILES

OC(CCC/C=C\C/C=C\C[C@H]1[C@H](O1)C/C=C\CCCCC)=O
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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11S(12R)-EET Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11S(12R)-EET123931-40-8OthersInhibitorinhibitorinhibit

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