Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (5655):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W017462S

Creatine-d₅ monohydrate		99.93%
Creatine-d₅ (monohydrate) is the deuterium labeled Creatine monohydrate. Creatine monohydrate, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[1].

HY-W450789S

Phenylmethan-d₂-ol		≥99.0%
Phenylmethan-d₂-ol is the deuterium labeled Phenylmethan-ol[1].

HY-B0421S

Mycophenolic acid-d₃		98.95%
Mycophenolic acid-d₃ is deuterium labeled Mycophenolic acid, which is an an immunosuppresant agent and has potent anti-proliferative activity.

HY-42487S

Exatecan Intermediate 1-d₅		99.80%
Exatecan Intermediate 1-d₅ is the deuterium labeled Exatecan Intermediate 1.

HY-B0399S

L-Carnitine-d₉		≥99.0%
L-Carnitine-d₉ is the deuterium labeled L-Carnitine. L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2].

HY-N0067S1

γ-Aminobutyric acid-d₂		99.72%
γ-Aminobutyric acid-d₂ is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].

HY-Y0337S5

L-Cysteine-d₃		≥99.0%
L-Cysteine-d₃ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-W727879

Upadacitinib-¹⁵N,d₂
Upadacitinib-¹⁵N,d₂ (ABT-494-¹⁵N,d₂) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib-¹⁵N,d₂ (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC₅₀=43 nM). Upadacitinib-¹⁵N,d₂ (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib-¹⁵N,d₂ (ABT-494) can be used for several autoimmune disorders research.

HY-B0594S

Iohexol-d₅		99.97%
Iohexol-d₅ is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo[1].

HY-B1205S

(Rac)-Atropine-d₃		≥99.0%
(Rac)-Atropine-d₃ is the deuterium labeled (Rac)-Atropine[1].

HY-N7092S11

D-Fructose-d-1		≥98.0%
D-Fructose-d-1 is the deuterium labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].

HY-133152S

Brexpiprazole S-oxide-d₈		98.72%
Brexpiprazole S-oxide-d₈ is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM[1][2][3].

HY-113150S1

Hexanoylglycine-d₂		≥98.0%
Hexanoylglycine-d₂ is the deuterium labeled Hexanoylglycine[1].

HY-W016823S

p-Tyramine-d₄ hydrochloride		99.52%
p-Tyramine-d₄ (hydrochloride) is the deuterium labeled Tyramine hydrochloride. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1][2].

HY-115397

Aprepitant-d₄		≥99.0%
Aprepitant-d₄ is the deuterium labeled Aprepitant[1].

HY-77839S

Cortodoxone-d₅		≥99.0%
Cortodoxone-d₅ is the deuterium labeled Cortodoxone.

HY-134928AS

Pyridinium bisretinoid A2E-d₄ TFA
Pyridinium bisretinoid A2E-d₄ TFA is the deuterium-labeled Pyridinium bisretinoid A2E (HY-134928). Pyridinium bisretinoid A2E (A2E)is an initiator of blue-light-induced apoptosis. Photoactivation of Pyridinium bisretinoid A2E mediates autophagy and the production of reactive oxygen species.

HY-W244382

Alanine-2,3,3,3-d4		≥98.0%
Alanine-2,3,3,3-d4 is the deuterium labeled Alanine-2,3,3,3[1].

HY-W099602S

Dodecane-d₂₆		99.83%
Dodecane-d₂₆ is the deuterium labeled Dodecane[1].

HY-N0492S

α-Lipoic Acid-d₅
α-Lipoic Acid-d₅ is the deuterium labeled α-Lipoic Acid. α-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4].

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