2. Others Autophagy
  3. Isotope-Labeled Compounds Autophagy Mitophagy
  4. Iohexol-d5

Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo[1].

For research use only. We do not sell to patients.

Iohexol-d<sub>5</sub> Chemical Structure

Iohexol-d5 Chemical Structure

CAS No. : 928623-33-0

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Based on 1 publication(s) in Google Scholar

Other Forms of Iohexol-d5:

Iohexol-d5 Related Antibodies

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  • Purity & Documentation

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Description

Iohexol-d5 is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging in vivo[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Iohexol-d5 Related Antibodies
Molecular Weight

826.17

Formula

C19H21D5I3N3O9
CAS No.
Unlabeled Cas

66108-95-0
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C(I)C(N(C(C)=O)C([2H])([2H])C(O)([2H])C([2H])([2H])O)=C(I)C(C(NCC(O)CO)=O)=C1I)NCC(O)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (60.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (60.52 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2104 mL 6.0520 mL 12.1040 mL
5 mM 0.2421 mL 1.2104 mL 2.4208 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 1.2104 mL 6.0520 mL 12.1040 mL 30.2601 mL
5 mM 0.2421 mL 1.2104 mL 2.4208 mL 6.0520 mL
10 mM 0.1210 mL 0.6052 mL 1.2104 mL 3.0260 mL
15 mM 0.0807 mL 0.4035 mL 0.8069 mL 2.0173 mL
20 mM 0.0605 mL 0.3026 mL 0.6052 mL 1.5130 mL
25 mM 0.0484 mL 0.2421 mL 0.4842 mL 1.2104 mL
30 mM 0.0403 mL 0.2017 mL 0.4035 mL 1.0087 mL
40 mM 0.0303 mL 0.1513 mL 0.3026 mL 0.7565 mL
50 mM 0.0242 mL 0.1210 mL 0.2421 mL 0.6052 mL
60 mM 0.0202 mL 0.1009 mL 0.2017 mL 0.5043 mL
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Iohexol-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Iohexol-d5928623-33-0Isotope-Labeled CompoundsAutophagyMitophagyMitochondrial AutophagyInhibitorinhibitorinhibit

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