2. Others
  3. Isotope-Labeled Compounds
  4. Yohimbine-d3

Yohimbine-d3 is the deuterium labeled Yohimbine (HY-12715).

For research use only. We do not sell to patients.

Yohimbine-d3 Chemical Structure

Yohimbine-d3 Chemical Structure

CAS No. : 133146-00-6

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5 mg USD 810 In-stock
10 mg USD 1300 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Yohimbine-d3:

Yohimbine-d3 Related Antibodies

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Description

Yohimbine-d3 is the deuterium labeled Yohimbine (HY-12715)[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Yohimbine-d3 Related Antibodies
Molecular Weight

357.46

Formula

C21H23D3N2O3
CAS No.
Unlabeled CAS

146-48-5
Appearance

Solid

Color

White to off-white

SMILES

[H][C@]12C(NC3=C4C=CC=C3)=C4CCN1C[C@@]5(CC[C@H](O)[C@H](C(OC([2H])([2H])[2H])=O)[C@]5(C2)[H])[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (13.99 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 1 mg/mL (2.80 mM; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7975 mL 13.9876 mL 27.9752 mL
5 mM 0.5595 mL 2.7975 mL 5.5950 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (258 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.7975 mL 13.9876 mL 27.9752 mL 69.9379 mL
DMSO 5 mM 0.5595 mL 2.7975 mL 5.5950 mL 13.9876 mL
10 mM 0.2798 mL 1.3988 mL 2.7975 mL 6.9938 mL
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Yohimbine-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Yohimbine-d3133146-00-6Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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