Uric acid-¹³C,¹⁵N₃

Name: Uric acid- 13 C, 15 N 3
Brand: MedChemExpress
SKU: HY-B2130S
Rating: 4.5 (1 reviews)

Cat. No.: HY-B2130S Purity: 99.20%: FAQs
Data Sheet SDS COA Handling Instructions

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Uric acid-¹³C,¹⁵N₃ is the ¹³C-labeled and ¹⁵N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[1][2].

For research use only. We do not sell to patients.

Uric acid-<sup>13</sup>C,<sup>15</sup>N<sub>3</sub> Chemical Structure

Uric acid-¹³C,¹⁵N₃ Chemical Structure

CAS No. : 2421217-23-2

Size	Price	Stock	Quantity
1 mg	USD 1480	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Uric acid-¹³C,¹⁵N₃:

Uric acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

172.08

Formula

C₄¹³CH₄N¹⁵N₃O₃

CAS No.

2421217-23-2

Unlabeled Cas

69-93-2

Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=C([15NH][13C]([15NH]1)=O)NC([15NH]2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

1M NaOH : 8.33 mg/mL (48.41 mM; ultrasonic and warming and adjust pH to 12 with 1M NaOH and heat to 60°C)

H2O : 6.25 mg/mL (36.32 mM; ultrasonic and adjust pH to 10 with 1M NaOH)

DMSO : 0.67 mg/mL (3.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8113 mL	29.0563 mL	58.1125 mL
5 mM	1.1623 mL	5.8113 mL	11.6225 mL
10 mM	0.5811 mL	2.9056 mL	5.8113 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.20%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (252 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 2020;50(4):359-375. [Content Brief]

[3]. Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32(11):1839-1845. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H2O / 1M NaOH	1 mM	5.8113 mL	29.0563 mL	58.1125 mL	145.2813 mL
H2O / 1M NaOH	5 mM	1.1623 mL	5.8113 mL	11.6225 mL	29.0563 mL
	10 mM	0.5811 mL	2.9056 mL	5.8113 mL	14.5281 mL
	15 mM	0.3874 mL	1.9371 mL	3.8742 mL	9.6854 mL
	20 mM	0.2906 mL	1.4528 mL	2.9056 mL	7.2641 mL
	25 mM	0.2325 mL	1.1623 mL	2.3245 mL	5.8113 mL
	30 mM	0.1937 mL	0.9685 mL	1.9371 mL	4.8427 mL
1M NaOH	40 mM	0.1453 mL	0.7264 mL	1.4528 mL	3.6320 mL